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Reversed-phase high-performance liquid chromatography (RP-HPLC) has become the most widely used method for pharmaceutical analysis, as it ensures accuracy, specificity and reproducibility for the quantification of drugs, while avoiding interference from any of the excipients that are normally present in pharmaceutical dosage forms. This book presents a simple methodology for developing stability-indicating methods and offers a ‘how-to guide’ to creating novel stability-indicating methods using liquid chromatography. It provides the detailed information needed to devise a stability-indicating method for drug substances and drug products that comply with international regulatory guidelines. As such, it is a must-read for anyone engaged in analytical and bioanalytical chemistry: professionals at reference, test, and control laboratories; students and academics at research laboratories, and scientists working for chemical, pharmaceutical, and biotechnology companies.
This book presents corpus-based research on functional syntax. It is the first book to present a comprehensive investigation into grammatical metaphor in English clause combining in large-size corpora. By providing a systematic illustration of features such as parataxis, hypotaxis and embedding, it fills a gap in the systemic functional literature. It also offers insights into testing grammatical metaphors using a corpus linguistics methodology. The book is a useful resource for anyone interested in writing development.
This edited volume focuses on the latest developments in classification and data science and covers a wide range of topics in the context of data analysis and related areas, e.g. the analysis of complex data, analysis of qualitative data, methods for high-dimensional data, dimensionality reduction, data visualization, multivariate statistical methods, and various applications to real data in the social sciences, medical sciences, and other disciplines. In addition to sharing theoretical and methodological findings, the book shows how to apply the proposed methods to a variety of problems — e.g. in consumer behavior, decision-making, marketing data and social network structures. Both method...
This open access book shares the experiences of Tropical Legumes III (TLIII) project in facilitating access to seed of improved legume varieties to smallholder farmers through innovation platforms. It highlights practices and guiding principles implemented in eight developing countries of sub-Saharan Africa and South Asia. This book details key processes that respective teams employed to create an innovation space that delivers seed, other inputs, knowledge and financial services to agricultural communities and most importantly, the underserved farmers in remote areas of the drylands. It offers valuable insights into the pathway to establishing, promoting and operating innovation platforms t...
This textbook highlights the engineering fundamentals and processing aspects of agricultural produce and covers important aspects of agro-processing and food engineering in one place. The chapters cover material handling, drying, size reduction process, mixing and forming, cleaning and separation, storage, and processing of cereals, pulses, oilseeds, fruit and vegetables, and their products. The book’s contents are systematically designed to provide a balanced overview of agro-processing techniques from the basic concepts to the case study, handling of the materials, and different unit operations. The systematic and simple elaboration of scientific aspects will make it unique and help to d...
Plants provide a source of survival for all life on this planet. They are able to capture solar energy and convert it into food, feed, wood and medicines. Though sessile in nature, over many millions of years, plants have diversified and evolved from lower to higher life forms, spreading from sea level to mountains, and adapting to different ecozones. They have learnt to cope with challenging environmental conditions and various abiotic and biotic factors. Plants have also developed systems for monitoring the changing environment and efficiently utilizing resources for growth, flowering and reproduction, as well as mechanisms to counter the impact of pests and diseases and to communicate wit...
This book describes the multitude of interactions between plant, soil, and micro-organisms. It emphasizes on how growth and development in plants, starting from seed germination, is heavily influenced by the soil type. It describes the interactions established by plants with soil and inhabitant microbial community. The chapters describe how plants selectively promote certain microorganisms in the rhizospheric ecozone to derive multifarious benefits such as nutrient acquisition and protection from diseases. The diversity of these rhizospheric microbes and their interactions with plants largely depend on plant genotype, soils attributes, and several abiotic and biotic factors. Most of the stud...
This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.
This contributed volume focuses on the effects of macro, meso, micro, and nanoplastic waste on marine biota. It discusses the threats posed by plastic waste on the flora and fauna in the marine environment. This book will help in understanding different aspects of plastic waste generation, its transportation with different natural and anthropogenic ways, its accumulation at the seacoast, and its impact on marine biota. The book also suggests strategies for saving marine life from threats posed by plastic waste and presents methods to reduce its generation using different strategies. This book is of interest to teachers, researchers, climate change scientists, capacity builders, and policymakers. It also serves as additional reading material for undergraduate and postgraduate students of Ecology, Botany, and Environmental Sciences.
This book focuses on interdisciplinary research in the field of biomedical engineering and neuroscience. Biomedical engineering is a vast field, ranging from bioengineering to brain-computer interfaces. The book explores the system-level function and dysfunction of the nervous system from scientific and engineering perspectives. The initial sections introduce readers to the physiology of the brain, and to the biomedical tools needed for diagnostics and effective therapies for various neurodegenerative and regenerative disorders. In turn, the book summarizes the biomedical interventions that are used to understand the neural mechanisms underlying empathy disorders, and reviews recent advances in biomedical engineering for rehabilitation in connection with neurodevelopmental disorders and brain injuries. Lastly, the book discusses innovations in machine learning and artificial intelligence for computer-aided disease diagnosis and treatment, as well as applications of nanotechnology in therapeutic neurology.