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This volume contains eight chapters that present both new and reviewed information fundamental to a clear understanding of lipid catabolism and transport at the molecular level. Three-dimensional structures of important serum lipoproteins, apolipoproteins, and lipases, utilizing X-ray data when available, are emphasized, and an attempt is made to relate structures to function. - Amphipathic helix - Apolipoprotein E - Lipophorin - Structure of serum albumin - Lipid binding proteins - Apolipoprotein B - Low-density lipoprotein
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In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improvements in patient organ function and hemopoietic capacity with increased hematocrit and quality of life. Using a new technology, vitamin E has now been successfully bound to the inner surface of a hollow-fiber membrane, so that the patient's blood is flowing in contact with a layer of antioxidant agent covering the inner surface of the membrane in the hemodialyzer. The opening chapters of this publ...
First multi-year cumulation covers six years: 1965-70.