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This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. • Applies analytical techniques to natural products research – an area of critical importance to drug discovery • Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics • Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail for both current practitioners and beginning researchers
Infections caused by Aspergillus spp. are associated with devastating mortality rates. Early and reliable diagnosis and subsequent rapid initiation of appropriate antifungal therapy has shown to improve survival significantly, at least for invasive Aspergillosis. Early diagnosis of Aspergillus associated infections, therefore, represents a cornerstone in successful management of these diseases. Current state of the art diagnostic approaches, new insights in epidemiology and established biomarkers as well as an outlook for future diagnostic options in the armamentarium of diagnostics tools are highlighted in this eBook.
Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.
Includes entries for maps and atlases.
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More than 250,000 courageous men and women were enlisted in the RCAF during World War II. They fought in all the major air operations. Thousands lost their lives. Only one in four aircrews completed their bomber tours: some were killed in action, some in training, others became prisoners of war. All volunteered. These are the stories of the valiant Canadians who fought in this brutal war.
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