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Pathobiology of Alzheimer's Disease
  • Language: en
  • Pages: 273

Pathobiology of Alzheimer's Disease

  • Type: Book
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  • Published: 1995-10-17
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  • Publisher: Elsevier

Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many...

Alzheimer's Disease
  • Language: en
  • Pages: 478

Alzheimer's Disease

  • Type: Book
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  • Published: 2006
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  • Publisher: IOS Press

"This is the book edition of the Journal of Alzheimer's Disease, Volume 9, No.3 Supplement (2006)"--T.p. verso.

Neuroscientific Basis of Dementia
  • Language: en
  • Pages: 294

Neuroscientific Basis of Dementia

In step with our growing lifespan, dementia is becoming a widespread handicap to the health and well-being of individuals and a burden on human society world-wide. The increasing prevalence of this tragic condition has stimulated an explosion of scientific research in the last ten years, which resulted in numerous profound insights and technical innovations. This timely volume presents both an overall and a detailed overview of the current worldwide knowledge about the neuroscientific basis of dementia. Leading authorities in their fields provide a far-reaching synthesis of all topics in dementia research, including pathogenesis of dementia, neuroimaging of the earliest alterations, potential biological and genetic markers for Alzheimer`s Disease and new therapeutic strategies. Each chapter discusses clinical implications and areas of controversy, highlights the wide range of current and future therapeutic possibilities and indicates promising directions for further research...

Stem Cells in Development and Disease
  • Language: en
  • Pages: 283

Stem Cells in Development and Disease

  • Type: Book
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  • Published: 2004-06-30
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  • Publisher: Elsevier

This volume of Current Topics in Developmental Biology showcases the research and therapeutic value of stem cells, and is proof of the increasing maturation of the fields of regenerative and molecular medicine. Reviews include:* Therapeutic cloning and tissue engineering to produce functional replacement tissues.* The role of the protein a-synuclein in a host of neurodegenerative diseases, which may be the first to benefit from stem cell therapy.* The curious array of functions in eukaryotic DNA methyltransferase, crucial for normal development and at the core of epigenetics regulation.* Influencing stem cell differentiation with mechanical stress, another example of genes versus the environ...

Biomedical Imaging
  • Language: en
  • Pages: 553

Biomedical Imaging

The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications - for instance - what properties are needed chemically and why? The topics covered in the book are: PET, SPECT, contrast agents, radioimaging/radionuclide conjugates, receptor mapping, small animal imaging (eg. WBAR - whole body autoradiography); photoinduced labelling, as well as chapters on the physical techniques used including: NMR, mass spectrometry and Xray. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.

The Molecular and Genetic Basis of Neurologic and Psychiatric Disease
  • Language: en
  • Pages: 930

The Molecular and Genetic Basis of Neurologic and Psychiatric Disease

Completely updated for its Fourth Edition, this book is the most comprehensive, current review of the molecular and genetic basis of neurologic and psychiatric diseases. More than 120 leading experts provide a fresh, new assessment of recent molecular, genetic, and genomic advances, offer new insights into disease pathogenesis, describe the newest available therapies, and explore promising areas of therapeutic development. This edition features an updated section on psychiatric disease and expanded, updated chapters on human genomics, gene therapy, and ethical issues. Six new chapters cover congenital myasthenic syndromes, hereditary spastic paraplegia, ion channel disorders, the phakomatoses, beta-galactosidase deficiency, and prion diseases. A Neurologic Gene Map describes the chromosome locus of all the genetic diseases and their gene product where known. The fully searchable online text will be available on a companion Website. (www.rosenbergneuroandpsychdisease.com)

Madness and Memory
  • Language: en
  • Pages: 344

Madness and Memory

The author, a 1997 recipient of the Noble Prize in medicine, describes the years he spent researching and demonstrating how the infectious proteins known as prions were responsible for brain diseases and how his theory has now become widely accepted in the science establishment.

Aluminium and Alzheimer's Disease
  • Language: en
  • Pages: 453

Aluminium and Alzheimer's Disease

  • Type: Book
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  • Published: 2001-07-03
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  • Publisher: Elsevier

The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to ...

Progress in Nucleic Acid Research and Molecular Biology
  • Language: en
  • Pages: 445

Progress in Nucleic Acid Research and Molecular Biology

- Provides a forum for discussion of new discoveries, approaches and ideas in molecular biology - Contributions from leaders in their fields - Abundant references