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Psychiatric Genetics
Psychiatric Genetics: A Primer for Clinical and Basic Scientists offers a straightforward introduction to the essentials of psychiatric genetics, covering basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of "take home" points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading.
Thomas Mann's Death in Venice
Study of the critical reception of one of the most famous and widely read works of modern literature. Thomas Mann's 1912 novella Death in Venice is one of the most famous and widely read texts in all of modern literature, raising such issues as beauty and decadence, eros and irony, and aesthetics and morality. The amount and variety of criticism on the work is enormous, and ranges from psychoanalytic criticism and readings inspired by Mann's own homosexuality to inquiries into the place of the novella in Mann's oeuvre, its structure and style, and its symbolism and politics. Critics have also drawn connections between the novella and works of Plato, Euripides, Goethe, Schopenhauer, Platen, W...
Behavioral Neurogenetics
This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.
Goethe Yearbook 14
Focuses on childhood in the Age of Goethe, in addition to various other topics and works. The Goethe Yearbook, first published in 1982, is a publication of the Goethe Society of North America and is dedicated to North American Goethe Scholarship. It aims above all to encourage and publish original English-language contributions to the understanding of Goethe and other authors of the Goethezeit, while also welcoming contributions from scholars around the world. Volume 14 features a special section on childhood in the Age of Goethe, co-edited with Anthony Krupp. In addition, readers will find two essays illuminating Goethe's Triumph der Empfindsamkeit, an inspired reading of Das Märchen again...
Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders
Next Generation Sequencing technology has been applied to clinical diagnoses in the past three to five years using various approaches, including target gene panels and whole exomes. The purpose of this book is to summarize the experiences, the results, advantages and disadvantages, along with future development in the area of NGS-based molecular diagnosis. This up-to-date volume will not only provide the readers working with Next Generation Sequencing the basics on how to apply the technology to molecular diagnosis, but will present the results and experience of practical application.
Autism
The book covers some of the key research developments in autism and brings together the current state of evidence on the neurobiologic understanding of this intriguing disorder. The pathogenetic mechanisms are explored by contributors from diverse perspectives including genetics, neuroimaging, neuroanatomy, neurophysiology, neurochemistry, neuroimmunology, neuroendocrinology, functional organization of the brain and clinical applications from the role of diet to vaccines. It is hoped that understanding these interconnected neurobiological systems, the programming of which is genetically modulated during neurodevelopment and mediated through a range of neuropeptides and interacting neurotrans...
Text, Lies and Cataloging
What do James Frey's A Million Little Pieces, Margaret B. Jones' Love and Consequence and Wanda Koolmatrie's My Own Sweet Time have in common? None of these popular books are what they appear to be. Frey's fraudulent drug addiction "memoir" was really a semi-fictional novel, Jones' chronicle of her life in a street gang was a complete fabrication, and Koolmatrie was not an Aboriginal woman removed from her family as a child, as in her seemingly autobiographical account, but rather a white taxi driver named Leon Carmen. Deceptive literary works mislead readers and present librarians with a dilemma. Whether making recommendations to patrons or creating catalog records, objectivity and accuracy are crucial--and can be difficult when a book's authorship or veracity is in doubt. This informative (and entertaining!) study addresses ethical considerations for deceptive works and proposes cataloging solutions that are provocative and designed to spark debate. An extensive annotated bibliography describes books that are not what they seem.
Algorithms for Computational Biology
This book constitutes the refereed proceedings of the First International Conference, AlCoB 2014, held in July 2014 in Tarragona, Spain. The 20 revised full papers were carefully reviewed and selected from 39 submissions. The scope of AlCoB includes topics of either theoretical or applied interest, namely: exact sequence analysis, approximate sequence analysis, pairwise sequence alignment, multiple sequence alignment, sequence assembly, genome rearrangement, regulatory motif finding, phylogeny reconstruction, phylogeny comparison, structure prediction, proteomics: molecular pathways, interaction networks, transcriptomics: splicing variants, isoform inference and quantification, differential analysis, next-generation sequencing: population genomics, metagenomics, metatranscriptomics, microbiome analysis, systems biology.
