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Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function, 2nd Edition
Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For example, cytochrome P450 proteins, which metabolize a vast array of drugs, steroids and other xenobiotics, are dependent on interactions with redox and allosteric partner proteins for their localization, stability, (catalytic) function and metabolic diversity (reactions). Genetic variations may impact such interactions by changing the splicing and/or amino acid sequence which in turn may impact protein topology, localization, post translational modifications and three dime...
The Physiologic Basis of Surgery
Established as a standard basic science text for surgeons and for residents preparing for the board exam, this authoritative text is written by renowned educators with experience preparing surgical residency curricula. The book presents complex physiologic concepts clearly, with numerous illustrations.
Research Grants
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Federation Proceedings
Vols. for 1942- include proceedings of the American Physiological Society.
