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Frontiers in Computational and Systems Biology
Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most comm...
A Practical Guide to Age-Period-Cohort Analysis
Age-Period-Cohort analysis has a wide range of applications, from chronic disease incidence and mortality data in public health and epidemiology, to many social events (birth, death, marriage, etc) in social sciences and demography, and most recently investment, healthcare and pension contribution in economics and finance. Although APC analysis has been studied for the past 40 years and a lot of methods have been developed, the identification problem has been a major hurdle in analyzing APC data, where the regression model has multiple estimators, leading to indetermination of parameters and temporal trends. A Practical Guide to Age-Period Cohort Analysis: The Identification Problem and Beyo...
Age-Period-Cohort Analysis
This book explores the ways in which statistical models, methods, and research designs can be used to open new possibilities for APC analysis. Within a single, consistent HAPC-GLMM statistical modeling framework, the authors synthesize APC models and methods for three research designs: age-by-time period tables of population rates or proportions, repeated cross-section sample surveys, and accelerated longitudinal panel studies. They show how the empirical application of the models to various problems leads to many fascinating findings on how outcome variables develop along the age, period, and cohort dimensions.
Amino Acids
Amino acid biochemistry and nutrition spans a broad range of fields including biochemistry, metabolism, physiology, immunology, reproduction, pathology, and cell biology. In the last half-century, there have been many conceptual and technical advancements, from analysis of amino acids by high-performance liquid chromatography and mass spectrometry
Youth Labor in Transition
Exacerbated by the Great Recession, youth transitions to employment and adulthood have become increasingly protracted, precarious, and differentiated by gender, ethnicity, and socioeconomic status. Youth Labor in Transition examines young people's integration into employment, alongside the decisions and consequences of migrating to find work and later returning home. The authors identify key policy challenges for the future related to NEETS, overeducation, self-employment, and ethnic differences in outcomes. This illustrates the need to encompass a wider understanding of youth employment and job insecurity by including an analysis of economic production and how it relates to social reproduct...
Financial Econometrics
Financial econometrics has developed into a very fruitful and vibrant research area in the last two decades. The availability of good data promotes research in this area, specially aided by online data and high-frequency data. These two characteristics of financial data also create challenges for researchers that are different from classical macro-econometric and micro-econometric problems. This Special Issue is dedicated to research topics that are relevant for analyzing financial data. We have gathered six articles under this theme.
Aging and the Life Course
Aging & the Life Course: Social & Cultural Contexts provides an accessible, up-to-date introduction to the study of aging and the life course from a distinctly sociological perspective. It explores the sociocultural dimensions of aging while encouraging critical thinking about the diversity of aging experiences, societal attitudes toward older adults, the politics and economics of growing old, and end-of-life resources. Throughout the text, Deborah Lowry emphasizes the relevance of the material for working with older populations, understanding social policy and policy debates, improving communities, relating to others, and understanding ourselves. Organized into four major sections, Part I introduces students to fundamental demographic, sociological, and life course concepts; part II explores the experiences and conditions of aging, especially in particular groups; and part III presents current research on older adults’ engagement in work, family, social networks, and sex. Finally, Part IV addresses themes of aging and social change.
Optimality
The volume presents a collection of refereed papers dealing with the issue of optimality in several areas including: multiple testing, transformation models, competing risks, regression trees, density estimation, copulas, and robustness.
A Practical Guide to Age-Period Cohort Analysis Using R
A popular and efficient tool to analyze grouped data of a certain event, APC analysis is used in a range of application areas, including public health, social science, demography, and economics. This book first describes the basic graphic presentation and modeling of APC data using R. Taking a more theoretical point of view, it then presents various methods for addressing the complex identification problem. Appendices cover the necessary background material.
