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THE HARRIS ORTHOPAEDIC LABORATORY @ The Mass General
The early endeavors of the Harris Orthopaedic Lab contributed significantly to widely diverse aspects such as the first human limb replantation, osteoporosis, the cause of osteoarthritis of the hip, and the environment of human articular cartilage. Subsequent years were focused on improving total hip replacement surgery, reducing its most common and devastating problems. These ranged from fatal pulmonary emboli thru poor implant design to solutions for arthritis from total developmental dislocation, and finally to unraveling the mysteries of and ultimately to the elimination of a strange and dreaded, world wide disease which destroyed the bone around total hip replacements in a million patients. Results: His works have contributed to extensive improvement in musculoskeletal disease including to the the reduction in every major complication of total hip surgery by an order of magnitude.
Vanishing Bone
Vanishing Bone unravels the mystery of a totally novel disease which causes the massive destruction of bone in individuals with total hip implants. Although initially considered 'rare, ' at its peak the disease affected over a million patients. This book takes readers through a detective adventure in contemporary medical science, identifying the cause of the disease the body's reaction to tiny wear particles from the prostheses, followed by the complex process of affecting its cure, the invention of a unique, wear-resistant plastic.
Essentials of Cemented Knee Arthroplasty
The Editors of “Essentials of Cemented Knee Arthroplasty” have compiled a comprehensive textbook on what many consider the most successful surgical procedure of the century. This book rounds out the compendium previously published by Springer on arthroplasty related topics: “The Well Cemented Total Hip Arthroplasty”, “PMMA Cements”, and “Management of Periprosthetic Joint Infection”. Unique to this text is the high quality contributions from over 160 world wide experts in the field, and provides a unique international perspective on the multifaceted topic of knee replacement surgery. Sections include a focus on Surgical Indications, Implant Design, Novel Technologies, Complications, and Cementing Technique, amongst others. Each Chapter not only draws on the most current literature on the subject, but also crystalizes the most important points into clinically relevant, practically applicable “take home messages”. This singular text is notable for not only its breadth, but also its depth, and will be an invaluable resource for knee arthroplasty surgeons throughout the globe.
First Exposure: Emergency Medicine
Designed for the medical student;s 4-week clerkship in the Emergency Department. This unique text helps the student learn the most clinically relevant material in a streamlined, easily-accessible format. Focuses on the "Don't Miss Diagnoses" and "Commonly Encountered Problems" that the student must master to succeed in their clerkship.
Annual Report
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Carcinogenic Potency Database; Endocrine Disruptors
Papers include: supp. to the carcinogenic potency database (CPD): results of animal bioassays published in 1993 to 1994; supplemental plot of the CPD; workshop on characterizing the effects of endocrine disruptors on human health at environmental exposure levels; an approach to the development of quantitative models to assess the effects of exposure to environmentally relevant levels of endocrine disruptors on homeostasis in adults; evaluating the effects of endocrine disruptors on endocrine function during development; and species, interindividual, and tissue specificity in endocrine signaling. Illustrated.
