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Comprehensive Natural Products II
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
Handbook of Molecular Descriptors
Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research. In recent years, various strategies have been developed to characterize and classify structural patterns by means of molecular descriptors. It has become possible not only to assess diversities or similarities of structure databases, but molecular descriptors also facilitate the identification of potential bioactive molecules from the rapidly increasing number of compound libraries. They even allow for a controlled de-novo design of new lead structures. This is the most comprehensive collection of molecular descriptors and presents a detailed review from the origins o...
Fundamental QSARs for Metal Ions
Fundamental QSARs for Metal Ions describes the basic and essential applications of quantitative structure–activity relationships (QSARs) for regulatory or industrial scientists who need to predict metal ion bioactivity. It includes 194 QSARs that have been used to predict metal ion toxicity and 86 QSARs that have been used to predict metal ion bioconcentration, biosorption, and binding. It is an excellent sourcebook for academic, industrial, and government scientists and policy makers, and provides a wealth of information on the biological and chemical activities of metal ions as they impact health and the environment. Fundamental QSARs for Metal Ions was designed for regulatory and regula...
Biomedical Materials and Diagnostic Devices
Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and uses The biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject. The chapters in the book seek to address progress in successful design strategies for biomedical mate...
Capabilities and Governance of Nanotechnology in the Developing World
The imperative for responsible innovation in the nanotechnology domain has inspired and provoked assorted views on its trajectory, potential implications as well as appropriate pathways for its development across a spectrum of stakeholders. These debates assume greater significance in the context of developing nations since harnessing the inherent potential of this transformational technology presumes the establishment of simultaneous capabilities to cutting-edge technological innovation as well as risk governance, regulation and public engagement in an environment challenged by limited resources, weak innovation systems and inadequate abilities for risk management.This book seeks to examine...
Selenium
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects.
Modern Poisons
Modern Poisons bridges the gap between traditional toxicology textbooks and journal articles on cutting-edge science. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts such as the dose-response relationship and goes on to show exactly how chemicals enter the body and elicit their toxic effect. Kolok then traces toxicology's development, from studies of endocrine-disrupting chemicals in toiletries to the emerging science on prions and epigenetics. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of--and curiosity about--this fast-changing field.
Environmental Nanopollutants
Offering a wide overview of the most recent research on environmental nanopollutants this book gives the reader a full picture of the research on nanoparticles in the environment.
Reservoir Ecotoxicology
Reservoir construction is the key strategy for water resource management. In recent years, the migration of pollutants and their transformation into the reservoir ecosystem has become a global problem. Intensified anthropogenic activities and unsustainable practices have amplified the pollutant levels in the reservoir. Therefore, this book intends to highlight environmental characteristics of the reservoir, study methods of ecotoxicology, and mechanistic toxicogenetic pathways of pollutants in the reservoir. Adverse outcome pathway (AOPs) model is used to elucidate toxicological effects of reservoir pollutants. Moreover, ecological and human health risks of the Three Gorges Reservoir (TGR), the largest power generation reservoir on earth, and its pollution status are also discussed.
Diffusive Gradients in Thin-Films for Environmental Measurements
An essential guide to the applications and usage of the diffusive gradients in thin-films (DGT) technique for students and professionals.
