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Foundations of Computational Intelligence Volume 4: Bio-Inspired Data Mining Theoretical Foundations and Applications Recent advances in the computing and electronics technology, particularly in sensor devices, databases and distributed systems, are leading to an exponential growth in the amount of data stored in databases. It has been estimated that this amount doubles every 20 years. For some applications, this increase is even steeper. Databases storing DNA sequence, for example, are doubling their size every 10 months. This growth is occurring in several applications areas besides bioinformatics, like financial transactions, government data, environmental mo- toring, satellite and medica...
This book constitutes the refereed proceedings of the 5th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2004, held in Exeter, UK, in August 2004. The 124 revised full papers presented were carefully reviewed and selected from 272 submissions. The papers are organized in topical sections on bioinformatics, data mining and knowledge engineering, learning algorithms and systems, financial engineering, and agent technologies.
Critical Analysis of Monoclonal Antibody Therapy in Transplantation provides a critical analysis of monoclonal antibody therapies in transplantation. The book presents diverse approaches to monoclonal antibody therapy in transplantation and addresses some of the serious obstacles that remain both in understanding these mechanisms and in successfully applying them in clinical situations. The background and rationale for OKT3 therapy are examined and an extensive clinical experience with OKT3 induction therapy in cardiac transplantation is reviewed. The book also examines the background and rationale for the use of anti-TcR (??), anti-IL-2R, and anti-LFA-1 monoclonal antibodies in clinical transplantations. Other topics include the use of monclonal antibodies to CD4 and CD8 for the induction of adult transplantation tolerance in rodents and the possibilities for applying anti-idiotypical strategies that have proven useful in autoimmunity models to transplant recipients. Researchers and basic scientists involved in this field will find the book a fascinating and useful resource for their investigations.
A proposal that computing is not merely a form of engineering but a scientific domain on a par with the physical, life, and social sciences. Computing is not simply about hardware or software, or calculation or applications. Computing, writes Paul Rosenbloom, is an exciting and diverse, yet remarkably coherent, scientific enterprise that is highly multidisciplinary yet maintains a unique core of its own. In On Computing, Rosenbloom proposes that computing is a great scientific domain on a par with the physical, life, and social sciences. Rosenbloom introduces a relational approach for understanding computing, conceptualizing it in terms of forms of interaction and implementation, to reveal t...
This book constitutes the refereed proceedings of the 4th International Conference on Artificial Immune Systems, ICARIS 2005, held in Banff, Alberta, Canada, in August 2005. The 37 revised full papers presented were carefully reviewed and selected from 68 submissions. The papers are organized in topical sections on conceptual, formal, and theoretical frameworks, immunoinformatics, theoretical and experimental studies on artificial immune systems, and applications of artificial immune systems.
This book constitutes the refereed proceedings of the 4th European Conference on Principles and Practice of Knowledge Discovery in Databases, PKDD 2000, held in Lyon, France in September 2000. The 86 revised papers included in the book correspond to the 29 oral presentations and 57 posters presented at the conference. They were carefully reviewed and selected from 147 submissions. The book offers topical sections on new directions, rules and trees, databases and reward-based learning, classification, association rules and exceptions, instance-based discovery, clustering, and time series analysis.
Cytokines are well characterized molecules that control the communication between cells. Their importance in immunology is very critical for the control of the quantity and of the quality of each specific response against foreign antigens (virus, bacteria, ...). When the cytokine network is mis-regulated disease can appear (autoimmunity, immunodeficiencies like in AIDS or cancer). This comprehensive treatment of this exciting area of molecular medicine presents an informative description of the major cytokines together with coverage of their role in the different parts of the immune system and of their implication in immunopathology, and will be of great interest to medical researchers and academics in the field. Industrial researchers with an interest in immunology will also find this book useful.
From the cheaply made "tax-shelter" films of the 1970s to the latest wave of contemporary "eco-horror," Canadian horror cinema has rarely received much critical attention. Gina Freitag and André Loiselle rectify that situation in The Canadian Horror Film with a series of thought-provoking reflections on Canada's "terror of the soul," a wasteland of docile damnation and prosaic pestilence where savage beasts and mad scientists rub elbows with pasty suburbanites, grumpy seamen, and baby-faced porn stars. Featuring chapters on Pontypool, Ginger Snaps, 1970s slasher films, Quebec horror, and the work of David Cronenberg, among many others, The Canadian Horror Film unearths the terrors hidden in the recesses of the Canadian psyche. It examines the highlights of more than a century of Canadian horror filmmaking and includes an extensive filmography to guide both scholars and enthusiasts alike through this treacherous terrain.