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The International Mining Forum is a meeting of scientists and professionals for exchanging new ideas and experiences, evaluate previously implemented solutions, and discuss fresh ideas that might change the mining industry’s image. In recent years theory and technology in mine safety and efficient exploitation has made considerable progress in China, Poland and other countries, due to the introduction of many new theories and technologies. The International Mining Forum 2010, jointly organized by Anhui University of Science and Technology (China), AGH University of Science and Technology (Poland) and Mineral and Energy Economy Research Institute of the Polish Academy of Sciences (Poland), has provided experts all over the world with an opportunity and platform to exchange information and ideas. Purpose of the forum was to promote research and development of mine safety, efficient exploitation theory and provide theoretical and technical support for mine safety improvement. This book is addressed to researchers and professionals who work in the fields of underground mining technology, rock engineering or mine management.
This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications. Due to their selective biocatalytic capabilities, enzymes are used in a broad range of industries and processes. The book highlights selected enzymes and their applications in agriculture, food processing and discoloration, as well as their role in biomedicine. In turn, it discusses biochemical engineering strategies such as enzyme immobilization, metabolic engineering, and cross-linkage of enzyme aggregates, and critically weighs their pros and cons. Offering a wealth of information, and stimulating further research by presenting new concepts on enzymatic catalytic functions in basic and applied contexts, the book represents a valuable asset for researchers from academia and industry who are engaged in biochemical engineering, microbiology and biotechnology.
In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes). Basic concepts and technologies describing in detail how these functional oligonucleotides can be identified are presented. Numerous examples demonstrate the versatility of in vitro selected oligonucleotides. Special emphasis has been put on a section that shows the broad applicability of aptamers, e. g. in target validation, for analytics, or as new therapeutics. This first overview in the field is of prime interest for a broad audience of scientists both in academia and in industry who wish to expand their knowledge on the potential of new oligonucleotide functions and their applications.
The key element of any fluorescence sensing or imaging technology is the fluorescence reporter, which transforms the information on molecular interactions and dynamics into measurable signals of fluorescence emission. This book, written by a team of frontline researchers, demonstrates the broad field of applications of fluorescence reporters, starting from nanoscopic properties of materials, such as self-assembled thin films, polymers and ionic liquids, through biological macromolecules and further to living cell, tissue and body imaging. Basic information on obtaining and interpreting experimental data is presented and recent progress in these practically important areas is highlighted. The book is addressed to a broad interdisciplinary audience.
This book reviews studies showing that interesting and useful molecular-scale switches and sensors can be made out of nucleic acids, by both artificial and natural means. The first section of the book is devoted to artificial nucleic acid switches and sensors. In second section, three chapters show that nature has been as crafty a molecular-scale engineer as any modern scientist, in the evolution of natural nucleic acid switches and sensors.
As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular BiologyTM series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results. Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead.
DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DN...
When Ren Wei was brought into the study, his expression was extremely unsightly. None of the three Gu brothers had martial arts below him. The three brothers surrounded him, and he had no strength to fight back, let alone there was an Old Elder beside him. Ren Wei could only helplessly accept the bondage. He was tied up by Gu Er with a buffalo tendon rope, and his two hands were tied behind his back. He could still walk naturally, even if he only relied on his two legs, normally more than ten young men would not be able to get close to him, but anyone in this study room was not an ordinary young man, especially Yang Fan. Ren Wei understood clearly how brilliant Yang Fan's martial arts were. Even if Yang Fan did not have a weapon in his hand, and he could grab any weapon that was most convenient, he was still not Yang Fan's opponent.