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Drug Delivery
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery
Biomedical Nanomaterials
The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.
Oral Bioavailability and Drug Delivery
ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability...
Pharmacological Aspects of Essential Oils
Pharmacological Aspects of Essential Oils: Current and Future Trends provides a collection of therapeutic and pharmacological applications of the most researched essential oils of great importance derived from Clove, Cinnamon, Coriander, Turmeric, Thymus zygis, Thyme vulgaris, Ocimum basilicum, Copaifera spp, and Nigella sativa species. The new approach towards using a metal phenolic network with the essential oils as a tool of nanomedicine will surely open a new horizon for the research community. Treating disorders such as diabetes, insomnia, and obesity with essential oils will provide a new area of research. Aromatherapy, which is creating a market especially in the personal health care ...
Women in China from Earliest Times to the Present
This essential reference work provides an alphabetic listing, with an extensive index, of studies on women in China from earliest times to the present day written in Western languages, primarily English, French, German, and Italian. Containing more than 2500 citations of books, chapters in books, and articles, especially those published in the last thirty years, and more than 100 titles of doctoral dissertations and Masters theses, it covers works written in the disciplines of anthropology and sociology; art and archaeology; demography; economics; education; fashion; film and media studies; history; interdisciplinary studies; law; literature; music; medicine, science, and technology; political science; and religion and philosophy. It also contains many citations of studies of women in Hong Kong and Taiwan.
Experimental Models of Epilepsy and Related Comorbidities
Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.
Carbon Monoxide in Drug Discovery
CARBON MONOXIDE IN DRUG DISCOVERY An insightful reference for the latest physiological and therapeutic studies of carbon monoxide In Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential, a team of distinguished authors delivers foundational knowledge, the latest research, and remaining challenges regarding the physiological roles and therapeutic efficacy of carbon monoxide (CO). The editors have included a broad selection of resources from leading experts in the field that discuss the background and physiological roles of CO, a variety of delivery forms including CO prodrugs using benign carriers, CO sensing, therapeutic applications, and clinical trials. Organi...
Hydrogen Sulfide
HYDROGEN SULFIDE Covers H2S interactions, methods of detection and delivery in biological environments, and a wide range of applications Research on hydrogen sulfide (H2S) spans diverse disciplines including chemistry, biology, and physiology. In recent years, new materials and approaches have been developed to deliver H2S and related reactive sulfur species in various clinical contexts. Although many biological pathways involving H2S are complex, all are governed by fundamental chemical interactions between reactive sulfur species and other molecular entities. Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies provides the foundation req...
Plant Bioactives and Drug Discovery
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound is...
