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The Molecular Basis of Programmed Cell Death and Neuroinflammation in Neurodegenerative Diseases
Age-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuroinflammation as well as neuronal degeneration. Apoptosis, necrosis, and autophagy are all types of programmed cell death that are morphologically distinct from one another. Over the last decade, extensive research has been conducted on necroptosis, resulting in a better understanding of its molecular underpinnings and role in neurodegenerative diseases. A later study investigates the processes of apoptosis and necroptosis, as well as their roles in the activation of inflammatory immune responses. Although there is a distinct mode of cell death with distinct morphol...
Endoplasmic Reticulum Stress Response and Transcriptional Reprogramming
Endoplasmic reticulum (ER) is an intracellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. A number of biochemical, physiological, or pathological stimuli can interrupt protein folding process, causing accumulation of unfolded or misfolded proteins in the ER lumen, a condition called “ER stress”. To cope with accumulation of unfolded or misfolded proteins, the ER has evolved a group of signaling pathways termed “Unfolded Protein Response (UPR)” or “ER stress response” to align cellular physiology. To maintain ER homeostasis, transcriptional regulation mediated through multiple UPR branches is orchestrated to increase...
Hua Yan (1682-1756) and the Making of the Artist in Early Modern China
Hua Yan (1682-1756) and the Making of the Artist in Early Modern China explores the relationships between the artist, local society, and artistic practice during the Qing dynasty (1644–1911). Arranged as an investigation of the artist Hua Yan’s work at a pivotal moment in eighteenth-century society, this book considers his paintings and poetry in early eighteenth-century Hangzhou, mid-eighteenth-century Yangzhou, and finally their nineteenth-century afterlife in Shanghai. By investigating Hua Yan’s struggle as a marginalized artist—both at his time and in the canon of Chinese art—this study draws attention to the implications of seeing and being seen as an artist in early modern China.
A Story of Ruins
This richly illustrated book examines the changing significance of ruins as vehicles for cultural memory in Chinese art and visual culture from ancient times to the present. The story of ruins in China is different from but connected to “ruin culture” in the West. This book explores indigenous Chinese concepts of ruins and their visual manifestations, as well as the complex historical interactions between China and the West since the eighteenth century. Wu Hung leads us through an array of traditional and contemporary visual materials, including painting, architecture, photography, prints, and cinema. A Story of Ruins shows how ruins are integral to traditional Chinese culture in both ar...
Immortal Primordial World
Creation Immortal Emperor: Immortal Emperor Sky Tyrant has been dead for ten thousand years, no one can defeat him. With a single sword strike, Heaven and Earth will be destroyed. The Heavenly Emperor of Wei was extremely talented, his Eight Devils Mysterious Eyes overlooked the ancient river, and his killing power was the highest in the world. Meng Xuan, is killing them a small task? Meng Xuan: I can't say it was a small matter, right? That would seem too arrogant. Interesting, right? There were 3,000 great Daos, 100,000 Planets, and various types of Chosen vying for the Emperor's Road. ...
Curriculum Studies in China
Scholars from three continents collaborate to create a truly global understanding of curriculum in the world's most populous country. This book discusses major topics in curriculum studies in China and shows how Chinese scholars understand their field's history, circumstances, and place in a globalized world.
Information Engineering and Applications
In past twenty years or so, information technology has influenced and changed every aspect of our lives and our cultures. Without various IT-based applications, we would find it difficult to keep information stored securely, to process information and business efficiently, and to communicate information conveniently. In the future world, ITs and information engineering will play a very important role in convergence of computing, communication, business and all other computational sciences and application and it also will influence the future world's various areas, including science, engineering, industry, business, law, politics, culture and medicine. The International Conference on Informat...
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