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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Guest edited by Dr. Margaret E. Wierman, this issue of Endocrinology and Metabolism Clinics will cover several key areas of interest related to Androgens in Women. This issue is one of four selected each year by our series Consulting Editor, Dr. Adriana Ioachimescu. Articles in this issue include but are not limited to: Hyperandrogenic Anovulation: Differential Diagnosis and Evaluation, Diagnosis of Polycystic Ovary Syndrome, Polycystic Ovary Syndrome: Ontogeny in Adolescence, Fertility Issues in Polycystic Ovarian Disease: A Systematic Approach, Management of Women with PCOS during Pregnancy, Genetics of PCOS, Cardiometabolic Risk in PCOS: Current Guidelines, Non Classical Congenital Adrenal Hyperplasia, Post-menopausal Hyperandrogenism: Evaluation and Treatment Strategies, Sexual Dysfunction in Women, Use of Testosterone in Postmenopausal women, Risks of Testosterone Therapy in Women, Non-Classic Congenital Adrenal Hyperplasia, and more.
In this vivid and timely history, Juan Cole tells the story of Napoleon's invasion of Egypt. Revealing the young general's reasons for leading the expedition against Egypt in 1798 and showcasing his fascinating views of the Orient, Cole delves into the psychology of the military titan and his entourage. He paints a multi-faceted portrait of the daily travails of the soldiers in Napoleon's army, including how they imagined Egypt, how their expectations differed from what they found, and how they grappled with military challenges in a foreign land. Cole ultimately reveals how Napoleon's invasion, the first modern attempt to invade the Arab world, invented and crystallized the rhetoric of liberal imperialism.
This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
Islamic counselling is a form of counselling which incorporates spirituality into the therapeutic process. Until now there has been little material available on the subject with no one agreed definition of Islamic counselling and what it involves. There has also been a rapidly growing population of Muslims in Western societies with a corresponding rise in need of psychological and counselling services. Islamic Counselling: An Introduction to theory and practice presents a basic understanding of Islamic counselling for counsellors and Islamic counsellors, and provides an understanding of counselling approaches congruent with Islamic beliefs and practices from a faith-based perspective. The bo...
The bestselling guide to the vagus nerve, now in 20+ languages: unlock the self-healing power of Stephen Porges’s Polyvagal Theory Vagus exercises for reducing anxiety, healing trauma, and rebalancing your autonomic nervous system This comprehensive guide offers an easy-to-understand overview of the vagus nerve—and helps you unlock your body’s innate capacity to heal from stress, trauma, anxiety, and injury. Dr. Stanley Rosenberg, PhD, dispels long-held myths about the autonomic nervous system (ANS) and offers up-to-date research on how our physical health, emotional wellness, and the vagus nerve are all interconnected. Most importantly, he shows how these insights can help you heal yo...
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
This book is a product of the need of understanding the new debates from the perspective of business studies. First part includes the topics that define some of the contemporary issues in accounting, as well as demonstrate how accounting practices change to adapt necessities of time. Part II deals with contemporary marketing topics indicating the importance of consumer in today’s business and the necessity of understanding consumers. Finally, the last part of the book, includes writing related to new methods and approaches in operation management and production that gain importance parallel to development in industry.
Urban areas have been caught up in a turbulent process of transformation over the past 50 years and changes have been rapid, with issues such as mobility, nature, water management, energy use and public space featuring prominently._x000D_ In each Olympic year since 1988, the Faculty of Architecture at Delft University of Technology has held an international conference focusing on the connection between research and design, exploring the field of tension between science, technology and art._x000D_ This book presents the proceedings of the latest in this series of conferences: New Urban Configurations, held in Delft, the Netherlands, in October 2012 in collaboration with the European Associati...
This volume presents new research on royal courts from antiquity to the modern world, from Asia to Europe. It addresses the interactions of rulers and and elites at court, as well as the multiple connections between court, capital, and realm.