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Laron Syndrome - From Man to Mouse
Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. Together, this book condenses, consolidates, compares, and contrasts data derived from the human and mouse LS experiences and provides a unique resource for clinical and basic scientists to evaluate and compare IGF-I and GH actions.
My Sweet Heart
“As gripping as a thriller and accessible for people without any scientific education,” wrote the biggest Swedish broadsheet, Dagens Nyheter, when My Sweet Heart was released in 2012. The book has been fundamental in the rise of the low-carb movement in Sweden, where the debate surrounding low-fat diets has been raging for almost a decade. Inspired by a woman with type 2 diabetes who, using a strict low-carb diet, was able to stop taking insulin injections and lost 42 kilos in weight, science writer Ann Fernholm, PhD in Molecular Biotechnology, started to examine the science behind low-fat dietary advice. Why should people who need injections to reduce blood sugar fill their plates with ...
The Man Behind the Syndrome
The Man Behind the Syndrome by my friends and colleagues Peter and Greta Beighton is a delightful book which will be read eagedy and with keen intellectual pleasure by all human, medical, and dinical genetieists. The reader with a historical tum of mind will note right away that the book achieyes more than the usual entry in a dictionary of seientific biography. In addition to the standard professional data, it gives a photo and some personal glimpses of the man, allowing the reader to appreeiate his human qualities as weIl. This volume contains, so to speak, the creme de la creme, namely, those in a group whose names are daily on the lips of every practicing dinical geneticist. This interesting and instructive book is commended to all in medical genetics and the history of medieine with the highest enthusiasm and gratitude to its authors for undertaking this labor of love. A second volume is planned for more recently delineated disorders for which an eponym is not yet widely used.
Current Catalog
Includes subject section, name section, and 1968-1970, technical reports.
National Library of Medicine Current Catalog
First multi-year cumulation covers six years: 1965-70.
Mosby's Dictionary of Medicine, Nursing & Health Professions
So much more than just a bestselling dictionary, Mosby's Dictionary of Medicine, Nursing & Health Professions, 9th Edition is a one-stop reference to help you make sense of the complex world of health care. It features over 56,000 authoritative definitions, 45 appendixes, a color atlas of the human body, online resources, and more than 2,450 full-color illustrations - nearly three times more than any other dictionary available - making it an indispensible reference for students and professionals alike. UNIQUE! More than 2,450 color photographs and line drawings demonstrate and explain complex conditions and abstract concepts. A Color Atlas of Human Anatomy contains 43 pages of clearly labele...
Hormone Research
None
Hormone Resistance Syndromes
Leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. Hormone Resistance Syndromes provides an authoritative summary and standard reference for all those clinicians and researchers actively studying these mutations today and affords a unique opportunity to understand hormone action in normal physiology.
Encyclopedia of Molecular Mechanisms of Disease
This comprehensive encyclopedia supplies the reader with concise information on the molecular pathophysiology of disease. Entries include defined diseases (such as Parkinson's disease) as well as pathophysiological entities (such as tremor). The 1,200 essays are brilliantly structured to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by up to five references. Individual entries are written by leading experts in the respective area of research to ensure state-of-the-art descriptions of the mechanisms involved. It is an invaluable companion for clinicians and scientists in all medical disciplines.
Insulin-like Growth Factor Receptor Signalling
Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development, the insulin-like growth factor system also has important roles in a wide variety of pathological states. This has led to interest in the therapeutic potential of insulin-like growth factors and their binding proteins as candidate drug targets. This comprehensive book contains current information on both basic science and clinical aspects of IGFs and their regulatory proteins, with emphasis on their relevance to cancer.
