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Toxicology in the Use, Misuse, and Abuse of Food, Drugs, and Chemicals
Many chemotherapeutic agents introduced for use in humans are carcinogenic in laboratory animals (Conklin et al. 1965; Shimkin et al. 1966; Griswold et al. 1968; Harris 1976). However, initially their beneficial effect in disseminated cancer was of such short duration that the inevitable death of the patient from his primary disease precluded any clinical manifestation of the carcinogenic potential. During the last decade, chemotherapy has radically changed the outlook for many patients with cancer. Combinations of drugs, administered as the primary treatment, have resulted in high rates of cure in patients with disseminated malignancies, such as stage IV Hodgkin's disease or childhood acute...
Phytochemical Resources for Medicine and Agriculture
This book was tbe result of a symposium beld at tbe American Cbernical Society meeting in Miami Beacb, Florida, September 10-15, 1989. The symposium was jointly sponsored by Tbe Society for Economfc Botany and tbe American Cbernical Society Food and Natural Product sub division. Tbere were five speakers. During tbe social sessions (mostly over drinks in abotel room), it became obvious tbat, regardless of tbe discipline, we were all speaking tbe same language. Yet, prior to tbe symposium, only a few of tbe participants knew one anotber. We decided to expand tbe symposium into a book. The book would, we boped, accomplish for otbers wbat we bad discovered in ourselves. That is, the field of Nat...
Disease Prevention and Treatment
Place of publication transcribed from publisher's web site.
Sleep Science
"Roughly one third of our lifetime is - or should be - spent asleep; yet despite the expansive scientific knowledge gained in many fields (i.e., psychology, neurophysiology) about our wake state, only relatively recently have we begun to catch up with the study of sleep. As Tom Roth, former editor of the journal Sleep, put it, "It's analogous to going to Mars with a third of the Earth's surface still unexplored" [1].Sleep is a strange experience, playing tricks on our consciousness. Sometimes within only a couple minutes of dozing off, we can go through a plethora of vivid and complex experiences. Alternatively, we may lapse into what feels like a total absence of consciousness, a jump in time, waking after a long slumber with no memory of the last eight hours. Sleep does not bend time, but without a doubt, it alters our consciousness. It is, therefore, no surprise that most people enjoy sleeping - when we sleep, we no longer feel the toothache, headache or the heartache that we suffer when awake"--
The Circadian Clock
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy...
Chemogenomics in Drug Discovery
Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and leading pharmaceutical companies, this is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery process.
A Lower Ladakhi Version of the Kesar Saga
Tibetan Text, English Abstracts And Notes Bibliotheca Indica 1905-41
Water-soluble Resins
Authoritative survey of the natural, modified, and synthetic water-soluble resins and gums now available commercially.
World Lexicon of Grammaticalization
Based on analysis of more than 1,000 languages, this volume reconstructs more than 500 processes of grammatical change in the languages of the world.
Dictionary of Medical Acronyms and Abbreviations
This dictionary lists acronyms and abbreviations occurring with a reasonable frequency in the literature of medicine and the health care professions. Abbreviations and acronyms are given in capital letters, with no punctuation, and with concise definitions. The beginning sections also include symbols, genetic symbols, and the Greek alphabet and symbols.
