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Comprehensive Toxicology
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Macro-engineering Seawater in Unique Environments
The subjects refer to histories of ancient and modern use of seacoasts; possible macro-projects capable of massive changes in the coastlines of the Dead Sea, Red Sea and Persian Gulf caused by canal and massively scaled hydropower dam installations; relevant macro-projects for the Black Sea and Baltic Sea; possibilities of refreshment of the Aral Sea and Iran’s Lake Uremia with seawater or river freshwater importation macro-projects; potential rehabilitation of some vital arid zone regions now dominated by moving or movable surface granular materials using unique and unusual macro-projects; seawater flooding of land regions situated below present-day global sea-level; harnessing energy and obtaining freshwater from the world’s salt-laden ocean by modern industrial means; various macro-projects designed specifically for the protection (reduction of vulnerability) of particular Earth geographical regions.
Gonadotropic Hormones
Hormonal Proteins and Peptides, Volume XI: Gonadotropic Hormones deals with gonad stimulating hormones that cause precocious sexual maturity. This book begins by reviewing the relationship of the chemical structure to the biological activity of gonadotropins and chorionic hormones, followed by a brief presentation on the in vitro bioassay methods. A comprehensive discussion on some aspects of the molecular mechanism of gonadotropin action is also provided. This publication concludes with an analysis of the immunobiology of gonadotropins. This book is intended for endocirnologists, but is also useful for medical practitioners and researchers concerned with gonadotropic hormones.
Human Physiology
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Male Infertility
Twenty five years ago the subject of male infertility scarcely existed in urological practice. At that time semen analysis was a rather cursory microscopic test, the scope of endocrine and hormone tests was limited and debate about the relevance of a varicocele was only just beginning. Since then, progress has owed about as much to sociological change as medical progress. Acceptance that problems of fertility should be shared between partners is now no longer questioned and the willingness of both husband and wife to recognise this and to seek help has been an important change in clinical practice. This book is concerned primarily with male infertility and it will be evident that this is now...
Hormone Toxicity in the Newborn
The account of "neonatal sterilization" is the story of the advocates of direct effect of steroids on the gonads and those who believed in the indirect influence, mediated through the hypothalamus and/or the pituitary gland. As often happens in biology, both convictions represent the same image seen from different perspectives. Prof DC Johnson (Kansas City, KS) reminisced the beginning of the story in a letter to me. I am paraphrasing parts of the letter with his permission. "As a starting point we could pick the life-long research of Emil Steinach ... " Steinach recognized the influence of testes on the develop ment of accessory sex organs in 1894, described virilization of females and femi...
Population Sciences
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Target Organ Toxicity
This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
