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This book highlights the analysis of new azimuth-independent methods of Stokes polarimetry and Mueller-matrix reconstruction of distributions of optical anisotropy parameters using spatial-frequency filtering of manifestations of phase (linear and circular birefringence) and amplitude (linear and circular dichroism) anisotropy for diagnosing changes in the orientational-phase structure of fibrillar networks of histological sections of biological tissues and polycrystalline films of biological fluids.
This book provides an essential overview of the basic principles of imaging modalities, accompanied by examples of their applications in modern clinical and associated pre-clinical studies. The monograph is based on the original results of investigation of the efficiency use of laser light and Mueller-matrix polarimetry approach for assessment of myocardial tissues towards confirmation the cause of death. A morphological analysis of necrotic changes in the myocardial tissue of patients that died due to heart attack, coronary heart disease and acute coronary insufficiency was carried out and the data and histological sections of the myocardium inspected utilizing Mueller-matrix mapping of tis...
"What are the recent developments in the field of Metrology?" International leading experts answer this question providing both state of the art presentation and a road map to the future of measurement science. The book is organized in six sections according to the areas of expertise, namely: Introduction; Length, Distance and Surface; Voltage, Current and Frequency; Optics; Time and Relativity; Biology and Medicine. Theoretical basis and applications are explained in accurate and comprehensive manner, providing a valuable reference to researchers and professionals.
This book presents a new diagnostic approach that utilizes complex statistical, correlation, fractal, and singular analysis of spatial distribution of the Stokes vector of scattered polarized light in different diffraction zones. The technique is able to identify changes in the distribution of optical axes and the birefringent indices of multi-layered fibrillar networks of biological tissues. The book also presents various scenarios for the formation of polarization singularities in laser speckle images of phase-inhomogeneous, multi-layered biological tissues in terms of the characteristic values of Mueller-matrix images. Moreover, in the context of potential diagnostic applications, it discusses the states of polarization singularities and their changes associated with the pathological abnormalities of the extracellular matrix of human tissues, its spatial peculiarities and structural orientation.
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This b...
For many centuries, mankind has tried to learn about his health. Initially, during the pre-technological period, he could only rely on his senses. Then there were simple tools to help the senses. The breakthrough turned out to be the discovery of X-rays, which gave insight into the human body. Contemporary medical diagnostics are increasingly supported by information technology, which for example offers a very thorough analysis of the tissue image or the pathology differentiation. It also offers possibilities for very early preventive diagnosis. Under the influence of information technology, 'traditional' diagnostic techniques and new ones are changing. More and more often the same methods c...
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
Carboxylic Ortho Acid Derivatives: Preparation and Synthetic Applications discusses the principal classes of ortho acid derivatives and their preparation, properties, and reactions. The book is a critical survey and attempts to collate literature regarding the wide array of information on ortho acid derivatives to be of use to chemists studying different sorts of problems. The text is divided into seven chapters, where Chapter 1 begins with a discussion of the general concepts of carboxylic ortho esters, their synthesis, and properties. Chapters 2 to 4 tackle reactions of ortho esters that result to different bonds and bond formations such as (a) carbon-oxygen and carbon-halogen bond, (b) carbon-nitrogen or carbon-phosphorus, and (c) carbon-carbon or carbon-hydrogen bond formation. Chapter 5 discusses the synthesis, properties, and applications of carbohydrate ortho esters. Related compounds and their properties, preparation, and chemical transformations are the topic of Chapters 6 and 7. Some of these compounds are trithioorthocarboxylates, tetrathioorthocarbonates, and amide acetals. The book is a valuable reference to students or anyone else interested in chemistry.
The Handbook of Photonics for Biomedical Science analyzes achievements, new trends, and perspectives of photonics in its application to biomedicine. With contributions from world-renowned experts in the field, the handbook describes advanced biophotonics methods and techniques intensively developed in recent years.Addressing the latest problems in