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Enzyme Functionality serves as a conduit for trailblazing research in enzyme engineering-relating current understanding of sequence families, the new notion of enzyme structure classes, and modern methods in protein engineering, design, and directed evolution to accelerate the development of novel enzyme functionalities. This reference gathers the diverse perspectives of nearly 80 scientists from around the globe and surveys all leading rational and random approaches to the artificial evolution of enzymes. Citing more than 1500 notable works, it outlines assays for enzyme activity, stability, and specificity and a wide variety of site-directed, redesign, and evolutionary engineering methods.
Despite the overuse of the word in movies, political speeches, and news reports, "evil" is generally seen as either flagrant rhetoric or else an outdated concept: a medieval holdover with no bearing on our complex everyday reality. In "A Philosophy of Evil," however, acclaimed philosopher Lars Svendsen argues that evil remains a concrete moral problem: that we're all its victims, and all guilty of committing evil acts. "It's normal to be evil," he writes--the problem is, we have lost the vocabulary to talk about it. Taking up this problem--how do we speak about evil?--"A Philosophy of Evil" treats evil as an ordinary aspect of contemporary life, with implications that are moral, practical, and above all, political. Because, as Svendsen says, "Evil should neither be justified nor explained away--evil must be fought."
The Complete Book of the Donkey contains invaluable advice on all aspects of the care and welfare of donkeys. Sections include advice on buying and caring for donkeys, their diet, pasture management, breeding and showing.
Am account of boredom, something that we have all suffered from, yet actually know very little about.
"Loki is a divisive figure in American heathenry and his wife Sigyn is all but forgotten ... why is Loki a problem in American culture? This book will provide varying perspectives from established heathens from both academic and practical standpoints, rituals/devotional practices for honoring Loki and Sigyn, and personal anecdotes and communications from my long, wild ride with the Norse gods"--
This book is intended as an introductory textbook for graduate students and as a reference book for engineers and scientists working in the field of coastal engineering. As such it gives a description of the theories for wave and nearshore hydrodynamics. It is meant to de-mystify the topics and hence starts at a fairly basic level. It requires knowledge of fluid mechanics equivalent to a first year graduate level. At the end of each topic, an attempt is made to give an overview of the present stage of the scientific development in that area with numerous references for further studies.
Lars Svendsen draws upon the writings of thinkers from Adam Smith to Roland Barthes to analyze fashion as both a historical phenomenon and a philosophy of aesthetics.
For many of us it is the ultimate fear: to die alone. Loneliness is a difficult subject to address because it has such negative connotations in our intensely social world. But the truth is that wherever there are people, there is loneliness. You can be lonely sitting in the quiet of your home, in the still of an afternoon park, or even when surrounded by throngs of people on a busy street. One need only turn on the radio to hear a crooner telling us just how lonesome we can be. In this groundbreaking book, philosopher Lars Svendsen confronts loneliness head on, investigating both the negative and positive sides of this most human of emotions. Drawing on the latest research in philosophy, psy...
The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.