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Skeletal Muscle
Provides readers with a detailed understanding of the different facets of muscle physiology. Examines motoneuron and muscle structure and function. It is intended for those need to know about skeletal muscle--from undergraduate and graduate students gaining advanced knowledge in kinesiology to physiotherapists, physiatrists, and other professionals whose work demands understanding of muscle form and function.
Galvani's Spark
Galvani's Spark describes the gradual understanding of the nerve impulse. Proceeding from a chance observation on a frog leg, to studies on squid giant axons and bacteria, this book concludes with the increasing realization that ion channells are responsible for a variety of clinical disorders.
Sherrington's Loom
How does the brain create consciousness? How is it that we have a sense of self; a self that can identify thousands of people, places, objects, words, and musical melodies? While the ultimate challenge--that of transforming electrical impulses in nerve cells into sensations, thoughts, and actions--remains a mystery, there is a great deal that is now known about the way the brain functions. Further, that knowledge is increasing through the use of ever more powerful experimental methods. Sherrington's Loom brings the key information together by blending crucial historical discoveries with more recent findings in the laboratory and neurological clinic. This book is a "must-have" for anyone interested in the history of medicine and science, and who is eager for insights as to how the conscious brain may work.
Neuromuscular Function and Disorders
Neuromuscular Function and Disorders focuses on the various processes underlying disordered neuromuscular function. Topics covered include the nature of membrane defects in myotonia and familial periodic paralysis; the disorder of neuromuscular transmission responsible for myasthenia gravis and the various pseudo-myasthenic syndromes; and the disorders of Schwann cell function which cause demyelination. This book is comprised of 28 chapters divided into two sections and begins with a discussion on the normal anatomy and physiology of peripheral nerve and muscle. Included in the first section are descriptions of the ionic mechanisms responsible for the resting and action potentials of nerve a...
Fatigue
This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.
The Laidback Lifestyle Anyone Can Have It
The Laidback Lifestyle is about being happy. Have you ever wondered why some people are happy and others are not? It's not about money because there are a lot of unhappy people in the world with money. Happiness is "LIVING LIFE ON YOUR TERMS." All you need are some basic principles to follow each day. It doesn't have to be complicated. In fact, It's mandatory that you do not make it complicated. If you make it complicated it defeats the whole purpose. The Laidback Lifestyle is a simple, easy-to-read book with tips on how you can increase your productivity all while minimizing the stress in your life. Work smarter and not harder. It's about the attitude and mindset. Obviously, there are many ...
Aranzio's Seahorse and the Search for Memory and Consciousness
In the final volume of his historical neuroscience trilogy, prize-winning author Alan J. McComas recounts the research that led to recognition of the hippocampus, a structure deep within the brain, as being primarily responsible for memory. This intriguing and exciting account includes observations on patients with memory loss as well as insights from ingenious laboratory experiments. Using several arguments in support, McComas suggests that it is the electrical impulse activity of neurons in the hippocampus that creates consciousness and that the latter is, in fact, the ever-changing sequence of short-term memories. He show us how a deeper knowledge of the hippocampus can help us develop a fuller understanding of Alzheimer's disease and other disorders of memory and behaviour, including 'long COVID. Lavishly illustrated, Aranzio's Seahorse will be of value not only to neuroscientists, psychologists, and philosophers but to all those interested in the workings of the brain and in the history of its exploration.
Biological Reactive Intermediates V
Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the research featured in the Fifth International Symposium on Biological Reactive Intermediates (BRI V). The grou...
Muscle, Matrix, and Bladder Function
This conference and monograph were the result of many collective efforts. The whole concept was formulated one early Wednesday morning at our weekly research meeting at Children's Hospital in our division of urology. We have been most fortunate to have a close collaboration with Bob Levin, Ed Macarak, and Pam Howard who have helped steer the course of our division's growing interest in basic science. At our weekly meetings our laboratory fellow will summarize their current work. Other ongoing areas of investigation in our labs and elsewhere are discussed. We have always made an effort to try and understand what other groups are doing who are working in the area of bladder smooth muscle resea...
Exercise Physiology
This history of exercise physiology is written from a systems perspective. It examines the responses of key physiological systems to the conditions of acute and chronic exercise, as well as their coupling with integrative responses.
