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The aim of this collection of articles is to assemble advances in stem cell-based approaches and their application to the study of parasitic diseases. Tropical parasites, including unicellular protozoan organisms and helminths, represent a major public health burden, particularly in tropical regions of the world. The study of these organisms is significantly hampered by the lack of effective in vitro/ ex vivo culture systems that mimic natural conditions and facilitate a thorough understanding of parasite development and host-parasite interactions. The advent of stem cell technology offers the opportunity to derive the right cell types to culture these parasites. Moreover, stem cell-derived organoids accurately reproduce the particular niche in which the parasites grow, develop, interact with host tissues and reproduce. In addition, particularly for helminths (i.e., multicellular parasites), the identification and characterisation of the parasite’s stem cell system, will be critical to complement our current and future understanding of fundamental biological processes, such as worm maturation, and interaction with the host immune system and microbiota.
Studies in Natural Products Chemistry: Bioactive Natural Products (Part I) contains articles written by leading authorities in their respective fields of research. It presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. - Volume 28 is part of a great family of useful reference books - Illustrates the types of critical discoveries that emerge from the interface of chemistry and biology - Contributions are from well-respected authors
Do spiders get thirsty? How long would it take a cow to fill the Grand Canyon with milk? How do they get the stripes on toothpaste? Plus other questions answered. Do Polar Bears Get Lonely? is the third compilation of readers' answers to the questions in the 'Last Word' column of New Scientist , the world's best-selling science weekly. This latest collection includes a bumper crop of wise and wonderful answers never before seen in book form. As usual, the simplest questions often have the most complex answers - while some that seem the knottiest have very simple explanations.
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A Sunday Times bestseller How long is 'now'? The short answer is 'somewhere between 2 and 3 seconds'. The long answer involves an incredible journey through neuroscience, our subconscious and the time-bending power of meditation. Living in the present may never feel the same. Ready for some more? Okay. Why isn't Pluto a planet? Why are dogs' noses wet? Why do hens cluck more loudly after laying an egg? What happens when one black hole swallows another? Do our fingerprints change as we get older? How young can you die of old age? And what is at the very edge of the Universe? Life is full of mind-bending questions. And, as books like What If? and Why Don't Penguins' Feet Freeze? have shown, the route to find each answer can take us on the weirdest and most wonderful journeys. How Long is Now? is a fascinating new collection of questions you never thought to ask, along with answers that will change the way you see everything.
„Jakieś dwie–trzy sekundy” – brzmi krótka odpowiedź. Nieco dłuższa wymaga zagłębienia się w neurobiologię, mechanizmy podświadomości i medytacyjną percepcję czasu. Przekonajcie się, że teraźniejszość może mieć zupełnie inne oblicze! Dlaczego nie kichamy podczas snu? Co sprawiło, że Pluton przestał być planetą? Skąd się biorą bąbelki? Czy cząstki elementarne mogą mieć kolor? Jak młodo można umrzeć ze starości? Co się dzieje, kiedy jedna czarna dziura wchłania drugą? I czy odciski palców człowieka zmieniają się z wiekiem? Życie często podsuwa nam zadziwiające pytania. Kiedy poszukujemy odpowiedzi, wyruszamy we wspaniałą, pełną przygód i zasadzek podróż. Jak długo trwa teraz? to najnowsza książka niezwykle popularnej serii magazynu New Scientist, znanej polskim czytelnikom m.in. z bestsellera „Dlaczego pingwinom nie zamarzają stopy?”. Znajdziecie tu dosłownie wszystko: od fal grawitacyjnych po wspomnienia złotej rybki. Będziecie się dobrze bawić i niepostrzeżenie przyswoicie sporą dawkę wiedzy z różnych dziedzin nauki.
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- Mengapa rambut dan jari kuku tetap tumbuh setelah manusia mati? - Mengapa sebagian orang bertangan kidal dan sebagian lain tidak? - Dapatkan virus dan bakteri disebarkan dari uang yang berganti-ganti tangan? - Berapa lama waktu yang diperlukan oleh rata- rata sapi untuk mengisi Grand Canyon dengan ‘ air susunya? - Berapa besarkah butir air hujan terbesar yang mungkin ada? - Berapa banyak jumlah leluhur Anda selama tiga puluh tahun generasi? - Apakah beruang kutub merasa kesepian? dan banyak pertanyaan lain... Buku ini hadir dengan jawaban dari pertanyaan paling aneh di dunia. Terkadang, pertanyaan yang terdengar konyol pun memiliki jawaban yang kompleks dan ilmiah. Tentunya, Anda akan terpuaskan karena ditunjang oleh bahasan ahli yang kompeten. Sembari menambah ilmu dan pengetahuan baru yang tak ternilai harganya. Anda akan terpingkal-pingkal saat membaca buku ini.
Cât durează ACUM? Răspunsul scurt este „undeva între două şi trei secunde“; răspunsul lung implică o călătorie prin neuroştiinţe, subconştientul nostru şi puterea de modificare a timpului căpătată prin meditaţie. Trăirea clipei prezente este posibil să nu mai fie niciodată aceeaşi. La prima vedere, australianul Terence Tao pare un om normal care predă matematica la University of California, Los Angeles. Dar nu este nici pe departe o persoană obișnuită. Conform Institutului Davidson din SUA, el are un IQ de 230, cel mai mare înregistrat vreodată. Cu alte cuvinte, Terence este cel mai deștept om din lume. Coeficientul mediu de inteligență se situează în jur...