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Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of re...
This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearanc...
Cabinets of prints and drawings are found in the earliest art collections of Early Modern Europe. From the sixteenth century onwards, some of them acquired such fame that the necessity for an ordered and scientific display meant that a dedicated keeper was occasionally employed to ensure that fellow enthusiasts, as well as visiting diplomats, courtiers and artists, might have access to the print room. Often collected and displayed together with drawings, the prints formed a substantial part of princely collections which sometimes achieved astounding longevity as a specialised group of collectibles, such as the Florentine Gabinetto Disegni e Stampe at the Uffizi (GDSU). Prints and drawings, b...
"Two celebrated and complementary collections of Rubens' sketches - in the Courtauld Institute of Art in London and The State Hermitage Museum, St Petersburg - are brought together to form the basis of this study of the artist's work." "Often regarded as one of the most compelling and remarkable aspects of the artist's work, Rubens' oil sketches reveal the genesis of many of his most important commissions. This book, published to coincide with a major exhibition at the Hermitage Rooms, Courtauld Institute of Art, focuses on Rubens' projects where the Hermitage and Courtauld holdings are exceptionally rich, including the ceiling of the Banqueting House at Whitehall, and the now lost ceiling of the Jesuit church in Antwerp. By bringing together preparatory material from a number of major commissions this book aims to provide a concentrated account of the role of the oil sketch in Rubens' work."--Jacket.
The Three Apostles of Russian Music looks at three figures in the Soviet avant-garde who led modernist music in the 1920s. Mosolov, Popov, and Roslavets were popular composers who are now unfortunately forgotten. These remarkable musicians produced compositions like the sensational machine music Foundry by Mosolov. The first symphony by Popov attracted musicians in Europe and America but was banned after the premiere, while Roslavets discovered serialism before Schoenberg, opening up a new trend in modernism. This book is the first study in English of the work, lives, and legacies of these “apostles” of the Russian avant-garde.
"The Collections of the Romanovs celebrates the 300th anniversary of the founding of St. Petersburg by exploring the role of the Romanov dynasty as collectors of fine and decorative arts. The book investigates in particular the historic role of St. Petersburg as Russia's window to the West, and features the great masterworks of Western European art collected and prized by Romanov tsars, from Peter the Great (who ruled from 1721-25) to the last of the dynasty, Nicholas II (who ruled from 1874-1918). Included are masterpieces of painting, drawing, printmaking, porcelain, silver, and tapestry over one hundred works in all, drawn exclusively from the extraordinary collection of the State Hermitage Museum in St. Petersburg."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
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Monografie over de Delftse schilder en tekenaar, wiens werk afwijkt van tijdgenoten door een ongewoon expressieve, soms visionaire stijl met veel dramatische effecten.