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Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.
An increasing variety of biological problems involving resource management, conservation and environmental quality have been dealt with using the principles of population biology (defined to include population dynamics, genetics and certain aspects of community ecology). There appears to be a mixed record of successes and failures and almost no critical synthesis or reviews that have attempted to discuss the reasons and ways in which population biology, with its remarkable theoretical as well as experimental advances, could find more useful application in agriculture, forestry, fishery, medicine and resource and environmental management. This book provides examples of state-of-the-art applications by a distinguished group of researchers in several fields. The diversity of topics richly illustrates the scientific and economic breadth of their discussions as well as epistemological and comparative analyses by the authors and editors. Several principles and common themes are emphasized and both strengths and potential sources of uncertainty in applications are discussed. This volume will hopefully stimulate new interdisciplinary avenues of problem-solving research.
Novelist Emily Gerard (1849-1905) went with her husband, an officer in the Austrian army, to Transylvania for two years in 1883. Then part of the Austro-Hungarian Empire, today a region of western Romania, Transylvania was little known to readers back in England. In the years following, she wrote this full-length account (published in 1888) as well as several articles on the region, which Bram Stoker used when researching the setting for Dracula. She describes encounters with the different nationalities that made up the Transylvanian people: Romanians, Saxons and gypsies. Full of startling anecdotes and written in a novelistic style, her work combines her personal recollections with a detailed account of the landscape and people. The second volume covers the gypsy and Jewish populations, as well as Gerard's mixed feelings on leaving the country. For more information on this author, see http://orlando.cambridge.org/public/svPeople?person_id=geraem.
This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical implications. The book will provide a comprehensive summary of the cellular and molecular biology of somatostatin and its recently isolated receptors. The book will review the design and use of specific somatostatin analogues both biochemically to characterize the specific functions of somatostatin and clinically in the treatment of various tumors.