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Ex Vivo Engineering of the Tumor Microenvironment
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
Advances in Stem Cell Research
Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
Stem Cells and Regenerative Medicine
As the world’s population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Eu...
Biomimetic Microengineering
This book will examine the relevant biological subjects involved in biomimetic microengineering as well as the design and implementation methods of such engineered microdevices. Physiological topics covered include regeneration of complex responses of our body on a cellular, tissue, organ, and inter-organ level. Technological concepts in cell and tissue engineering, stem cell biology, microbiology, biomechanics, materials science, micro- and nanotechnology, and synthetic biology are highlighted to increase understanding of the transdisciplinary methods used to create the more complex, robust biomimetic engineered models. The effectiveness of the new bioinspired microphysiological systems as ...
3D Printing Applications in Cardiovascular Medicine
3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes. - Addresses the novel technology and cardiac and vascular application of 3D printing - Features case studies and tips for applying 3D technology into clinical practice - Includes an accompanying website that provides 3D examples from cardiovascular clinicians, imagers, computer science and engineering experts
Acute Leukemias
Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.
The Hundred Years' War on Palestine
THE SUNDAY TIMES AND NEW YORK TIMES BESTSELLER 'Riveting and original ... a work enriched by solid scholarship, vivid personal experience, and acute appreciation of the concerns and aspirations of the contending parties in this deeply unequal conflict ' Noam Chomsky The twentieth century for Palestine and the Palestinians has been a century of denial: denial of statehood, denial of nationhood and denial of history. The Hundred Years War on Palestine is Rashid Khalidi's powerful response. Drawing on his family archives, he reclaims the fundamental right of any people: to narrate their history on their own terms. Beginning in the final days of the Ottoman Empire, Khalidi reveals nascent Palest...
Medicinal Plants
This book provides a comprehensive overview of medicinal plants and their interaction with abiotic stress in terms of morphological, physiological, biochemical, and molecular variations, and explains the adaptation and tolerance mechanisms involved. It presents various mechanisms that become operative in medicinal plants to combat stressful situations. The book discusses the secondary metabolites and/or bioactive compounds produced in medicinal plants under abiotic stress conditions, and the use of biostimulants and/or phytoprotectants to alleviate the adverse effects of abiotic stresses on medicinal plants. Additionally, it is likely to address opportunities and challenges in molecular and omics studies of medicinal plants under abiotic stress conditions. Overall, the chapters are developed by eminent subject experts with due care and clarity and cover an up-to-date literature review with relevant illustrations. The book would cater to the need of graduate and post-graduate students, researchers as well as scientists, and may attract the attention of pharmaceutical companies/industrialists and health policymakers.
Iran and the Surrounding World
These essays examine Iran’s place in the world--its relations and cultural interactions with its immediate neighbors and with empires and superpowers from the beginning of the Safavid period in 1501 to the present day. The book provides important historical background on recent political and social developments in Iran and on its contemporary foreign relations. The topics explored include Iranian influence abroad on political organization, religion, literature, art, and diplomacy, as well as Iran's absorption of foreign influences in these areas. A special focus is the prevailing political culture of Iran throughout its early modern and contemporary periods. The authors combine approaches from history, political science, anthropology, international relations, and culturalstudies. Some essays address Iran’s interactions with various Arab and Turkic ethnicities in the region stretching from India to Egypt. Others examine its relations with the West during the Qajar and Pahlavi eras, women's issues, culture inside Iran during the Islamic Republic, and the Shi`ite theocracy of Iran as compared with other Muslim states.
