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This book examines the regulatory framework for untested and unapproved uses (off-label uses) of medicines in the EU, UK, and USA. Before reaching patients, medicines are extensively tested by manufacturers and approved by regulators to minimise the risk of adverse reactions. However, physicians can prescribe pharmaceuticals for off-label uses, widespread in paediatrics, oncology, rare diseases and, more recently, in treatment for Covid-19. While off-label uses may offer hope, they may also expose patients to risks and uncertainties. Clarification is therefore needed to improve the protection of patients' rights while enhancing legal certainty for health actors. To this end, this work clarif...
This book provides a scientific and ethical approach to all forms of fraud and misconduct focusing on a scholarly however practice-oriented description of the problems, roots and potential solutions. Organized in dedicated parts, an international team of experts systematically analyzes the most prevalent forms of misconduct, ghost writing, pseudo-science, dubious trials, predatory journals, fake news, mistreatment and harassment, in research, publications, at academic institutions, and in the professional and healthcare environment. A special focus is given to corrective interventions and the role of prevention, education and training. Comprehensive in its scope, the book offers an easy-to-r...
The imposition of strict liability in tort law is controversial, and its theoretical foundations are the object of vigorous debate. Why do or should we impose strict liability on employers for the torts committed by their employees, or on a person for the harm caused by their children, animals, activities, or things? In responding to this type of questions, legal actors rely on a wide variety of justifications. Justifying Strict Liability explores, in a comparative perspective, the most significant arguments that are put forward to justify the imposition of strict liability in four legal systems, two common law, England and the United States, and two civil law, France and Italy. These justif...
Why the race to apply AI in psychiatry is so dangerous, and how to understand the new tech-driven psychiatric paradigm. AI psychiatrists promise to detect mental disorders with superhuman accuracy, provide affordable therapy for those who can’t afford or can’t access treatment, and even invent new psychiatric drugs. But the hype obscures an unnerving reality. In The Silicon Shrink, Daniel Oberhaus tells the inside story of how the quest to use AI in psychiatry has created the conditions to turn the world into an asylum. Most of these systems, he writes, have vanishingly little evidence that they improve patient outcomes, but the risks they pose have less to do with technological shortcom...
This Encyclopedia brings together jurists, computer scientists, and data analysts to map the emerging field of data science and law for the first time, uncovering the challenges, opportunities, and fault lines that arise as these groups are increasingly thrown together by expanding attempts to regulate and adapt to a data-driven world. It explains the concepts and tools at the crossroads of the many disciplines involved in data science and law, bridging scientific and applied domains. Entries span algorithmic fairness, consent, data protection, ethics, healthcare, machine learning, patents, surveillance, transparency and vulnerability.
This timely book discusses the application of the EU competition rules to pharmaceuticals, covering the prohibitions on anticompetitive agreements and abuse of dominance, and merger control. It carefully considers the balance between competition and innovation, as well as between competition and regulation, and concludes that competition and regulation are not alternatives, but complementary, and that novel ways of taking into account risk and real innovation through competition assessments have been developed.
İÇİNDEKİLER DENETİM KOMİTESİ ETKİNLİĞİNİN KURUMSAL YÖNETİM RAPORLARINA ETKİSİ: BİST’TE BİR UYGULAMA Nazan Güngör KARYAĞDI - Kadir GÖKOĞLAN ENTELEKTÜEL SERMAYENİN MUHASEBELEŞTİRİLMESİ Yakup ASLAN E-SPOR VE ELEKTRONİK SPORCULARIN VERGİLENDİRİLMESİ Seval ELDEN ÜRGÜP FİNANSAL FAİRPLAY UYGULAMALARI VE FİNANSAL RAPORLAMA ÜZERİNE BİR İNCELEME Uğur TATLI - İbrahim ÇEMBERLİTAŞ FUTBOL ENDÜSTRİSİNDE İNSAN KAYNAKLARININ MUHASEBELEŞTİRİLMESİ Fatih Ömür BİNİCİ - Fatma TEKTÜFEKÇİ FUTBOL KULÜPLERİNDE TRANSFER ÜCRETLERİNİN TÜRKİYE MUHASEBE STANDARTLARI ÇERÇEVESİNDE MUHASEBELEŞTİRİLMESİ Mert ÖNCEL FUTBOL KULÜPLERİNİN FİNANSAL PERFORMANSINI ETKİLEYEN FAKTÖRLER Ahmet AKATAK KÜRESEL EKONOMİ ve FUTBOL ENDÜSTRİSİ Turgay TOKSOY - Abdulkadir ATEŞ PROFESYONEL FUTBOL KULÜPLERİNİN GELİR KAYNAKLARI Lokman KARAGÖZ - Fırat AKYÜZ SPORCULARIN PROFESYONEL SPOR UYGULAMALARINDAN ELDE ETTİKLERİ GELİRLERİN TÜRKİYE VERGİ KANUNU KAPSAMINDA VERGİLENDİRİLMESİ Abdulkadir ATEŞ - Turgay TOKSOY UEFA HatTrick PROGRAMININ FİNANSAL AÇIDAN İNCELENMESİ Fırat AKYÜZ - Lokman KARAGÖZ
2022 NATIONAL INDIE EXCELLENCE AWARD FINALIST — BUSINESS, ENTREPRENEURSHIP, & SMALL BUSINESS • 2022 AXIOM BOOK AWARD BRONZE MEDALIST — ENTREPRENEURSHIP/SMALL BUSINESS • NAUTILUS BOOK AWARD SILVER WINNER — BUSINESS & LEADERSHIP “Redefining Rich is inspiring, thought-provoking, and highly recommended both as a fascinating story in its own right and as a call to reconsider what one truly aspires to in life.” —Midwest Book Review In our dysfunctional economy, “success” often comes at great personal cost . . . we’re tired, we’re stressed out, and we have no time for family and friends. It’s time to redefine “rich.” From a third-generation farmer and successful entrep...