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A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.
A multi-disciplinary overview, by leading authorities, of the influence of the work of Charles Darwin on arts, science and society.
The 9th International Symposium on Yersinia was held in Lexington, Kentucky, USA, in October 2006. Hundreds of Yersinia researchers from 18 countries gathered to present and discuss their research. In addition to 37 oral presentations, there were 150 poster presentations. This Symposium volume is based on selected presentations from the meeting and contains both reviews and research articles. It is divided into six topic areas that include genomics and pathogenesis.
This up-to-date guide focuses on the understanding of key regulatory mechanisms governing gene expression in Escherichia coli. Studies of E. coli not only provide the first models of gene regulation, but research continues to yield different control mechanisms.
A theory of human origins that is one-half Charles Darwin and one-half Cain and Abel is bound to entail a lot of rethinking of traditional themes. Rene Girard's thesis of original human violence and the Bible's power to reveal it has been around for more than a generation, but its consequences for Christian theology are still only slowly being unpacked. Anthony Bartlett's book makes a signal contribution, representing an astonishing leap forward in understanding what a biblical disclosure of founding violence means for Christian thought and life. If human language arose directly out of the primal experience of murder, then semiotics becomes a core area for theological examination. Tracing th...
From early studies of the plague causing agent through to comparatively more recent research defining aspects of the type III secretion mechanism, pathogenic Yersinia have served as an inventive model organism for researchers seeking to understand the complexities of bacteria-host cell interactions. In fact, seminal studies on Yersinia virulence mechanisms contributed to the emergence and recognition of the research field – cellular microbiology. Researching Yersinia infection biology continues to bring to light novel discoveries. Assortments of Yersinia whole genome sequencing projects are providing unparalleled insight into bacterial pathogen evolution and environmental adaptation. This ...
In this account of metrical stress theory, Bruce Hayes builds on the notion that stress constitutes linguistic rhythm—that stress patterns are rhythmically organized, and that formal structures proposed for rhythm can provide a suitable account of stress. Through an extensive typological survey of word stress rules that uncovers widespread asymmetries, he identifies a fundamental distinction between iambic and trochaic rhythm, called the "Iambic/Trochaic law," and argues that it has pervasive effects among the rules and structures responsible for stress. Hayes incorporates the iambic/trochaic opposition into a general theory of word stress assignment, intended to account for all languages ...
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THE DARWIN WARS is an entertaining, explanatory account of the evolution of today's neo-Darwinist theories, including the influential Selfish Gene theory - and the misunderstandings and even deep hatreds they provoke. The two scientific camps are currently divided between 'Dawkinsians' on the one hand, who may not agree with Richard Dawkins about very much but are convinced Stephen Jay Gould is dangerously wrong, and the 'Gouldians' on the other hand who take the opposite view. The two sides agree that Darwinian evolution explains the appearance and complexity of living beings. They disagree about almost everything else . . . Their vitriolic attacks might seem like academic storms in a teacup but in fact they are disputing our very nature and place in the world. For the first time, an impartial observer explains and evaluates the ideas that have transformed biology since the 1960s, their importance and the criticisms that have been made of them. Above all, THE DARWIN WARS shows the profound impact these theories have had on our beliefs and our culture.
This book explores the historical relations between science and religion and discusses contemporary issues with perspectives from cosmology, evolutionary biology and bioethics.