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Free Energy Calculations
  • Language: en
  • Pages: 528

Free Energy Calculations

This volume offers a coherent account of the concepts that underlie different approaches devised for the determination of free energies. It provides insight into the theoretical and computational foundations of the subject and presents relevant applications from molecular-level modeling and simulations of chemical and biological systems. The book is aimed at a broad readership of graduate students and researchers.

The Origin and Nature of Life on Earth
  • Language: en
  • Pages: 703

The Origin and Nature of Life on Earth

Uniting the foundations of physics and biology, this groundbreaking multidisciplinary and integrative book explores life as a planetary process.

Protocells
  • Language: en
  • Pages: 723

Protocells

  • Type: Book
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  • Published: 2022-06-07
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  • Publisher: MIT Press

The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells, known as protocells, are entities with lifelike properties created from nonliving materials, and the book provides in-depth investigations of processes at the interface between nonliving and living matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and proper...

Computational Biophysics of Membrane Proteins
  • Language: en
  • Pages: 274

Computational Biophysics of Membrane Proteins

Exploring current themes in modern computational and membrane protein biophysics, this book is ideal for researchers in computational chemistry and computational biophysics.

Membrane Permeability: 100 Years Since Ernest Overton
  • Language: en
  • Pages: 423

Membrane Permeability: 100 Years Since Ernest Overton

Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern conce...

Biophysical Analysis of Membrane Proteins
  • Language: en
  • Pages: 368

Biophysical Analysis of Membrane Proteins

Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new insights. Following an introduction, further sections discuss structural approaches, molecular interaction and large assemblies, dynamics and spectroscopies, finishing off with an exploration of structure-function relationships in whole cells.

Pacific Symposium on Biocomputing 2003
  • Language: en
  • Pages: 682

Pacific Symposium on Biocomputing 2003

The Pacific Symposium on Biocomputing (PSB 2003) is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. The rigorously peer-reviewed papers and presentations are collected in this archival proceedings volume. PSB 2003 brings together top researchers from the US, the Asia-Pacific region and around the world to exchange research findings and address open issues in all aspects of computational biology. PSB is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling and other computational methods, as applied t...

First Life
  • Language: en
  • Pages: 283

First Life

This pathbreaking book explores how life can begin, taking us from cosmic clouds of stardust, to volcanoes on Earth, to the modern chemistry laboratory. Seeking to understand life’s connection to the stars, David Deamer introduces astrobiology, a new scientific discipline that studies the origin and evolution of life on Earth and relates it to the birth and death of stars, planet formation, interfaces between minerals, water, and atmosphere, and the physics and chemistry of carbon compounds. Deamer argues that life began as systems of molecules that assembled into membrane-bound packages. These in turn provided an essential compartment in which more complex molecules assumed new functions required for the origin of life and the beginning of evolution. Deamer takes us from the vivid and unpromising chaos of the Earth four billion years ago up to the present and his own laboratory, where he contemplates the prospects for generating synthetic life. Engaging and accessible, First Life describes the scientific story of astrobiology while presenting a fascinating hypothesis to explain the origin of life.

Fourth Symposium on Chemical Evolution and the Origin and Evolution of Life
  • Language: en
  • Pages: 140

Fourth Symposium on Chemical Evolution and the Origin and Evolution of Life

  • Type: Book
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  • Published: 1991
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  • Publisher: Unknown

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Statistical Thermodynamics and Stochastic Kinetics
  • Language: en
  • Pages: 329

Statistical Thermodynamics and Stochastic Kinetics

Provides engineers with the knowledge they need to apply thermodynamics and solve engineering challenges at the molecular level.