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Mechanisms of Insulin Action
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
The Leatherback Turtle
The most comprehensive book ever written on leatherback sea turtles. Weighing as much as 2,000 pounds and reaching lengths of over seven feet, leatherback turtles are the world’s largest reptile. These unusual sea turtles have a thick, pliable shell that helps them to withstand great depths—they can swim more than one thousand meters below the surface in search of food. And what food source sustains these goliaths? Their diet consists almost exclusively of jellyfish, a meal they crisscross the oceans to find. Leatherbacks have been declining in recent decades, and some predict they will be gone by the end of this century. Why? Because of two primary factors: human redevelopment of nestin...
Annual Report
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Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
