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Recent Advances in Pediatric Cancer Predisposition Syndromes
We would like to acknowledge Dr. Giada Del Baldo and Dr. Mariachiara Lodi from IRCCS Bambino Gesù Children’s Hospital have acted as coordinator and have contributed to the preparation of the proposal for this Research Topic.
2021 WHO Classification of Pediatric Brain Tumors: A Final Wedding Between Morphology and Molecular Biology?
Tumors of the central nervous system (CNS) are a dramatic health problem due to their high morbidity and mortality in all ages. In the pediatric population, brain tumors constitute the second most common cancer diagnosed worldwide each year, accounting for approximately 25% of childhood cancers. Although there has been a moderate increase in survival rates for children with CNS tumors over the past decades, CNS tumors remain the second leading cause of cancer death in children less than 20 years of age. The fifth edition of the World Health Organization (WHO) Classification of Tumors of the Central Nervous System (WHO CNS5) was recently released. This builds on the 2016 WHO CNS tumor update,...
Pediatric Venous Thromboembolism
Venous thromboembolism (VTE) occurs less often in children than adults and therefore remains underrecognized despite increasing in incidence. Due to the risk of mortality, short- and long-term morbidity, and increased healthcare costs associated with pediatric VTE, this entity merits better understanding and consideration. With this Research Topic, we aim to highlight some special considerations of pediatric VTE, namely risk factors and epidemiology, rare types of pediatric thrombosis and considerations unique to specific clinical patient subgroups, approaches to management and treatment, and prevention
Pediatric CNS Tumors in Low- and Middle-Income Countries: Expanding our Understanding
Central nervous system (CNS) tumors represent about 20% of pediatric cancer cases worldwide and are the leading cause of cancer-related morbidity and mortality. In low- and middle-income countries, limited data suggests significant disparities in outcomes when compared to high-income countries. Nonetheless, this field is understudied and significant work needs to be done to further elucidate the epidemiology, clinical characteristics, and outcomes of this vulnerable population. In this Research Topic, we aim to describe recent advances in the biology, clinical, molecular, and health system characteristics of children and adolescents with CNS tumors. We welcome submissions of Original Researc...
Conventional Nuclear Medicine in Pediatrics
This superbly illustrated book combines the systematic approach of a textbook with the simplicity of consultation of an atlas in order to provide a comprehensive guide to the applications and benefits of scintigraphic studies in children. All of the clinical scenarios in which conventional nuclear medicine techniques frequently play a role in children are covered, with explanation of imaging diagnosis, the relevance of clinical history, problem solving, and pitfalls. The images themselves are the key focus of the book, and in each setting the added value offered by scintigraphy is carefully identified. The book also describes management of the pediatric patient and addresses general considerations, including reception, interaction with parents, radiopharmaceutical administration, image acquisition, radiation exposure, and the relationship of nuclear medicine and radiology. Since the child is not a young adult, it is insufficient simply to adapt nuclear medicine procedures performed in adults to the age and size of the child. Conventional Nuclear Medicine in Pediatrics will be a rich source of information for all who perform these procedures in the pediatric setting.
