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This book presents current laboratory, scientific and clinical aspects of nanomaterials used for medical applications in the fields of regenerative medicine, dentistry and pharmacy. It gives a broad overview of the in vitro compatibility assessment of nanostructured materials implemented in the medical field by the combination of classical biological protocols. The chapters cover all aspects of integrative medicine, such as green derived nanomaterials for biological applications; synthetic and nature-derived lipid nanoparticles and polymer nanoparticles.
This book presents the Proceedings of ICON–2019, an international meeting exclusively dedicated to nanostructured materials in medicinal applications. The conference emphasized the recent advances in multidisciplinary research on processing, morphol¬ogy, structure and properties of nanostructured materials and their applications in vari¬ous medicinal fields. The papers encompass basic studies and applications and address topics of novel issues, difficulties, and breakthroughs in the field of nanomedicine in cancer, tuberculosis, tissue engineering, regenerative medicine etc.
Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides rarely translatable into protein, which distinguishes them from small non-coding RNAs (sncRNAs) such as miRNAs, siRNAs, piRNAs, snoRNAs exRNAs, (scaRNAs). Long intervening/intergenic noncoding RNAs (lincRNAs) refer to lncRNA non-overlapped to protein-coding genes. In terms of abundance and specificity, ~30,000 lncRNAs have been identified in human tissues with ~ 10- fold lower abundance than mRNA. Near 80% of lncRNAs show tissue-specific features, in contrast to only less than 20% of mRNAs. In addition to tissue specificity, lncRNAs are also characterized by having significantly higher developmental stage specificity. Of the identified lncRNAs, although only a very small proportion have been validated to be biologically relevant, the emerging evidence has confirmed important regulatory functions at levels of transcription, post transcription, and epigenetic control. Physiologically, lncRNAs are involved in growth, development, reproduction, aging, and pathogenesis of disease initiation and progression, such as neurological disorders and cancers.
Since HIV was first identified in the early 1980s, we have had numerous scientific advancements to improve HIV prevention and treatment. However, there are still 38 million people currently living with HIV, and a proportion of them have developed Acquired Immunodeficiency Syndrome (AIDS). The main issue with HIV and AIDs is inequalities: the communities affected are disproportionately distributed among the Global South. World AIDS Day takes place every year on the 1st of December and was founded in 1988 — making it the first global health day to be established. This year, the theme of World AIDS Day is equality. Tackling the inequalities surrounding HIV testing, prevention, care, and stigma among marginalized populations is the only way to not fall behind the targets of the third sustainable development goal of ending the HIV/AIDS epidemic by 2030.
Several plant bioactives or plant-derived therapeutic molecules have been used against life-threatening diseases and their nanoparticle-mediated delivery greatly improves therapeutic efficacy. Advances in Phytonanotechnology for Treatment of Various Diseases aims to describe past and recent advances achieved in the field of phytonanotechnology. The chapters of this book provide thorough knowledge of medicinal plants, plant bioactives, plant extract-based nanoparticle synthesis, delivery of plant bioactives through nanoparticles, and their therapeutic activity against life-threatening diseases. This book focuses on the therapeutic activity of phytocomponents present in plants from diverse fam...
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