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The Cultural Identity and Education of University Students in Selected East-Central Countries
In Polish and Czech pedagogy, there have not been many studies on the social, cultural and educational functioning of academic youth in a culturally diversified environment. The analysis of identity behaviours presented by university students from the Polish-Czech borderland and of their learning potentialities will provide a chance for mutual recognition, understanding and the enrichment of both cultures – along with providing a chance for cultural sensitization. Due to the applied culturalization attitudes, this will also enhance the participation in the culture of the neighbouring country and the shortening of cultural distance. Such studies are also associated with a reflection upon the way in which a contemporary human understands cultural dimensions, the role they play in human life and the scope in which they shape the individual’s own and their social/cultural identity.
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Mathematics of Continuous and Discrete Dynamical Systems
This volume contains the proceedings of the AMS Special Session on Nonstandard Finite-Difference Discretizations and Nonlinear Oscillations, in honor of Ronald Mickens's 70th birthday, held January 9-10, 2013, in San Diego, CA. Included are papers on design and analysis of discrete-time and continuous-time dynamical systems arising in the natural and engineering sciences, in particular, the design of robust nonstandard finite-difference methods for solving continuous-time ordinary and partial differential equation models, the analytical and numerical study of models that undergo nonlinear oscillations, as well as the design of deterministic and stochastic models for epidemiological and ecolo...
Genomic Biomarkers for Pharmaceutical Development
Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters wri...
Happy ever after
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Spragnieni, by trwać. Tom 3
Kolejna część bestsellerowej serii "Spragnieni, by...!" Anna Szafrańska w mistrzowski sposób opowiada o drugich szansach, darowanych długach i pragnieniu, by żyć pełną piersią. Tessę, przyjaciółkę Alicji znanej ze Spragnionych, by żyć, i Piotra, brata Eweliny opisanej w Spragnionych, by kochać, połączył przypadek. I żadne z nich nie było z tego powodu zadowolone. Tessa chce przede wszystkim chronić przyjaciół, których uzależniony od narkotyków i alkoholu Piotr skrzywdził już wystarczająco. On jednak podjął walkę ze swoimi demonami i próbuje naprawić swoje życie. Czy Tessa może mu zaufać? Z biegiem czasu okazuje się, że łączy ich więcej, niż chcieliby przyznać... Ale zanim będą mogli być razem, Piotr musi odkupić swoje błędy, a Tessa – przekonać przyjaciół, by mu wybaczyli. Tylko jak, skoro ona też ich okłamała...? Ta historia poruszy nawet najbardziej nieczułe serca.
Genomic Biomarkers for Pharmaceutical Development
The focus of this chapter is on the development of miRNA diagnostics and the process for miRNA biomarker development. We discuss pancreatic cancer as a model for the application of miRNA-based tests in different clinical biopsy specimen types. Asuragen’s miRInform® Pancreas test illustrates the development of a laboratory developed test (LDT) that was validated in compliance with Clinical Laboratory Improvement Amendments (CLIA) and College of American Pathologists (CAP) regulations. We provide an overview of work on miRNA-based signatures which is focused on resolving clinical dilemmas in solid and cystic pancreatic lesions. We also review some of the promising miRNA candidates identified in biofluids from other cancer types. These studies highlight the emergence of miRNA-based diagnostic tools which have the potential to impact the clinical management of cancer by guiding early diagnosis, aiding in the assessment of patients’ prognosis, and enabling the identification of novel, more effective therapeutic targets.
Lilianna
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Tajemnice Kiliana
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Malvína
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