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Mechanisms underlying firing in healthy and sick human motoneurons
Since the latter half of the twentieth century an enormous amount of knowledge about mammalian motoneuron pools has been collected. This progress was enabled mostly by the development of the precise techniques of intracellular recordings in acute animal experiments, many of which were conducted under deep anaesthesia. Recently obtained evidence indicates that anaesthetics used at that times changed certain properties of the cell membrane, which might affect firing of the neuron. Experiments on normal humans gets around this problem, which lets one compare MN firing characteristics in humans and reduced preparations. Firing pattern of human motoneurons is obtained indirectly by recording from...
Sensorimotor Control of Movement and Posture
This collection of contributions on the subject of the neural mechanisms of sensorimotor control resulted from a conference held in Cairns, Australia, September 3-6, 2001. While the three of us were attending the International Union of Physiological Sciences (IUPS) Congress in St Petersburg, Russia, in 1997, we discussed the implications of the next Congress being awarded to New Zealand. We agreed to organise a satellite to this congress in an area of mutual interest -the neuroscience of movement and sensation. Australia has a long-standing and enviable reputation in the field of neural mechanisms of sensorimotor control. Arguably this reached its peak with the award of a Nobel Prize to Sir ...
Konrad Klapheck
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