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PET and SPECT of Neurobiological Systems
This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
Cell-Based Therapies in Stroke
Stroke remains one of the main causes of death and disability worldwide. While effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
Early Sound Recordings
The use of historical recordings as primary sources is relatively well established in both musicology and performance studies and has demonstrated how early recording technologies transformed the ways in which musicians and audiences engaged with music. This edited volume offers a timely snapshot of a wide range of contemporary research in the area of performance practice and performance histories, inviting readers to consider the wide range of research methods that are used in this ever-expanding area of scholarship. The volume brings together a diverse team of researchers who all use early recordings as their primary source to research performance in its broadest sense in a wide range of r...
The Age of Subtlety
A craze for intricate metaphors, referred to as conceits, permeated all forms of communication in seventeenth-century Italy and Spain, reshaping reality in highly creative ways. The Age of Subtlety: Nature and Rhetorical Conceits in Early Modern Europe situates itself at the crossroads of rhetoric, poetics, and the history of science, analyzing technical writings on conceits by such scholars as Baltasar Gracián, Matteo Peregrini, and Emanuele Tesauro against the background of debates on telescopic and microscopic vision, the generation of living beings, and the boundaries between the natural and the artificial. It contends that in order to understand conceits, we must locate them within the early modern culture of ingenuity that was also responsible for the engineer’s machines, the juggler’s sleight of hand, the wiles of the statesman, and the discovery of truths about nature.
Music and Cosmopolitanism
In Music and Cosmopolitanism, Cristina Magaldi examines music making in a past globalized world. This volume focuses on one city, Rio de Janeiro, and how it became part of a larger world through music and performance. Magaldi describes a process of creating connections beyond national borders, one that is familiar to contemporary city residents, but which was already dominant at the turn of the 20th century, as new technological developments led to alternative ways of making and experiencing music.
Advances in the Preclinical Study of Ischemic Stroke
This book reports innovations in the preclinical study of stroke, including - novel tools and findings in animal models of stroke, - novel biochemical mechanisms through which ischemic damage may be both generated and limited, - novel pathways to neuroprotection. Although hypothermia has been so far the sole "neuroprotection" treatment that has survived the translation from preclinical to clinical studies, progress in both preclinical studies and in the design of clinical trials will hopefully provide more and better treatments for ischemic stroke. This book aims at providing the preclinical scientist with innovative knowledge and tools to investigate novel mechanisms of, and treatments for, ischemic brain damage.
The Routledge Handbook to Spanish Film Music
The Routledge Handbook to Spanish Film Music provides a significant contribution to the research and history of Spanish film music, exploring the interdependence and ways in which discourses of sound and vision are constructed dialogically in Spanish cinema, with contributions from leading international researchers from Spain, the USA, the UK, France and Germany. Offering a multifocal and multidisciplinary study between related areas such as music studies, film studies and Spanish cultural studies, this book is divided into four sections, covering the early years of Spanish cinema; the 1940s and 1950s in Spanish cinema—the first decades of the Franco dictatorship; the importance of Fraga I...
From Formal Linguistic Theory to the Art of Historical Editions
Romance is a fertile ground for linguistic research. Instead of limiting their studies to one specialised area, some Romance scholars have managed to combine different aspects of the broad field of Romance linguistics in an impressive way. This volume is dedicated to the multifaceted research interests of Guido Mensching: Part 1 focusses on different aspects of the architecture of grammar and linguistic theory, covering Italian, Portuguese, French, Sardinian and Romance. The focus of Part 2 is on historical linguistics, discussing Old Occitan lexicography and Romance in Hebrew scripts. Part 3 is dedicated to aspects relating to plurilingualism, language contact and sociolinguistics. Part 4 explores research arguments that go beyond Romance philology but are nonetheless intertwined with it.
