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This book explores the importance of Single Nucleotide Polymorphisms (SNPs) in biomedical research. As SNP technologies have evolved from labor intensive, expensive, time-consuming processes to relatively inexpensive methods, SNP discovery has exploded. In terms of human biology, this research, particularly since the completion of the Human Genome Project, has provided a detailed understanding of evolutionary forces that have generated SNPs. It also has shown how SNPs shape human variation. The ability to inexpensively generate and analyze vast amounts of genetic data is poised to transform our understanding of human evolution and biology. “Single Nucleotide Polymorphisms” covers a broad...
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging...
The life and work of a leading Soviet physicist and an exploration of the strengths and weaknesses of Soviet science from Stalin through Gorbachev. In 2000, Russian scientist Zhores Alferov shared the Nobel Prize for Physics for his discovery of the heterojunction, a semiconductor device the practical applications of which include LEDs, rapid transistors, and the microchip. The Prize was the culmination of a career in Soviet science that spanned the eras of Stalin, Khrushchev, and Gorbachev—and continues today in the postcommunist Russia of Putin and Medvedev. In Lenin's Laureate, historian Paul Josephson tells the story of Alferov's life and work and examines the bureaucratic, economic, a...
The bibliography volume of the three-volume East Looks West: East European Travel Writing in Europe collates travel writing published in book form by east Europeans travelling in Europe from ca. 1550 to 2000. It is intended as a fundamental research tool, collecting together travel writings within each national/linguistic tradition, and enabling comparative analysis of such material. It fills an important gap in the existing reference literature, both in western and east European languages, and will be of use to those working in the growing fields of comparative travel writing, regional and national identities, and postcolonialism. These texts exist in surprisingly large numbers, and include...
This is a cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. This series is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. - Cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. - Brings to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.
Includes entries for maps and atlases.