Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
How Can Secretomics Help Unravel the Secrets of Plant-Microbe Interactions?
Secretomics describes the global study of proteins that are secreted by a cell, a tissue or an organism, and has recently emerged as a field for which interest is rapidly growing. The term secretome was first coined at the turn of the millennium and was defined to comprise not only the native secreted proteins released into the extracellular space but also the components of machineries for protein secretion. Two secretory pathways have been described in fungi: i) the canonical pathway through which proteins bearing a N-terminal peptide signal can traverse the endoplasmic reticulum and Golgi apparatus, and ii) the unconventional pathway for proteins lacking a peptide signal. Protein secretion...
Oxidative Stress and Redox Regulation
Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
The Changing Faces of Glutathione, a Cellular Protagonist
Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases. As a prototype antioxidant, it has been involved in cell protection from the noxious effect of excess oxidant stress, both directly and as a cofactor of glutathione peroxidases. In addition, it has long been known that GSH is capable of forming disulfide bonds with cysteine residues of proteins, and the relevance of this mechanism ("S-glutathionylation") in regulation of protein function has been well documented in a number of research fields. Rather paradoxically, it has also been high...
Thiol-based redox homeostasis and signalling
In contrast to the situation in heterotrophic organisms, plant genomes code for a significantly larger number of oxidoreductases such as thioredoxins (TRXs) and glutaredoxins (GRXs). These proteins provide a biochemical mechanism that allows the rapid and reversible activation or deactivation of protein functions in response to changing environmental conditions, as oxidative conditions caused by excessive photosynthesis. Indeed, owing to the fact that cysteines are sensitive to oxidation, TRXs and GRXs play an essential role in controlling the redox state of protein thiol groups. These redox-dependent post-translational modifications have proven to be critical for many cellular functions constituting regulatory, signalling or protective mechanisms. The articles contained in this Research Topic provide timely overviews and new insights into thiol-dependent redox regulation mechanisms with a focus on TRX- and GRX-based reduction systems in plants. The different contexts discussed take into account physiological, developmental and environmental conditions.
Biotrophic Plant-Microbe Interactions
Throughout their life, plants interact with all sorts of microbes. Some of these are detrimental and cause disease; some interactions are mutually beneficial for both partners. It is clear that most, if not all, of the interactions are regulated by highly complex checks and balances sustained by signalling and exchange of messengers and nutrients. The interactions where both partners are alive for a significant part of their time together are called biotrophic. In this e-book we bring together 33 articles representing the current state-of-the-art in research about diverse biotrophic plant-microbe associations aimed at describing and understanding how these complex and ubiquitous partnerships work and ultimately support much of the land-based biosphere.
Frontiers of Sulfur Metabolism in Plant Growth, Development, and Stress Response
Growing plants have a constitutive demand for sulfur to synthesize proteins, sulfolipids and other essential sulfur containing molecules for growth and development. The uptake and subsequent distribution of sulfate is regulated in response to demand and environmental cues. The importance of sulfate for plant growth and vigor and hence crop yield and nutritional quality for human and animal diets has been clearly recognized. The acquisition of sulfur by plants, however, has become an increasingly important concern for the agriculture due to the decreasing S-emissions from industrial sources and the consequent limitation of inputs from atmospheric deposition. Molecular characterization involvi...
The Babylonian Disputation Poems
In The Babylonian Disputation Poems Enrique Jiménez studies a group of ancient Babylonian poems that feature discussions between animals and trees. Using intertextual parallels and comparison with similar works in other literatures, he espouses a new classification of the Babylonian disputation poems as parodies. After examining neighboring traditions of literary disputation, he argues that the Babylonian poems influenced them, and that some may have been translated from Akkadian to Aramaic, from Aramaic and Syriac to Arabic. In addition, The Babylonian Disputation Poems provides editions of several previously unpublished Babylonian disputations, such as Palm and Vine and the Series of the Spider. It also offers the first edition of the latest known Babylonian fable, The Story of the Poor, Forlorn Wren. “The present book is an exemplary model for editing and commenting upon ancient texts, and almost every approach has been taken into account.” -Markham J. Geller, Journal for the Study of the Old Testament 43.5 (2019)
Contemporary Cognitive Therapy
Bringing together a stellar array of contributors whose work has been directly influenced by Aaron T. Beck, this volume presents current advances in cognitive therapy science and practice. Described are new and effective ways of understanding and treating clients suffering from a wide range of affective, anxiety, and personality disorders. The status of basic cognitive therapy principles and models is discussed, and important theoretical and clinical refinements are elaborated. Other topics include innovative applications for children and adolescents, couples, and families, as well as progress that has been made in integrating cognitive therapy with other treatments, such as pharmacotherapy.
