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**Selected for Doody's Core TitlesĀ® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics...
Thoene summarises the substantial work that has been accomplished in the treatment of inborn errors of metabolism with simple molecules. This handbook will enable interested clinician scientists to rapidly survey the field, thus ascertaining what has been done as well as future directions for therapeutic research. Its important introductory chapters discuss the infrastructure of the field. The book closely analyses the cofactors used to augment the function of defective enzymes and the compounds that are able to utilise an alternative pathway in order to avoid the consequences of the metabolic block present in the patient. Among other therapies, the authors discuss the use of zinc and tetrathiomolybdate to treat Wilson's disease and the use of cysteamine to treat nephropathic cystinosis.
Descriptions of programs in 58 American and Canadian medical schools. Such programs are available to physicians interested in clinical pharmacology and, specifically, in testing drugs on humans. Alphabetical arrangement by institutions. Each entry gives such information as program director, application proceedures, training support, description of the program, and the clinical and research facilities. Institution index.
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Principles and Practice of Clinical Research is a comprehensive text which addresses the theoretical and practical issues involved in conducting clinical research. This book is divided into three parts: ethical, regulatory, and legal issues; biostatistics and epidemiology; technology transfer, protocol development and funding. It is designed to fill a void in clinical research education and provides the necessary fundamentals for clinical investigators. It should be of particular benefit to all individuals engaged in clinical research, whether as physician or dental investigators, Ph.D. basic scientists, or members of the allied health professions, as well as both students and those actively participating in clinical research.Key Features* Comprehensive review ranging from a historical perspective to the current ethical, legal and social issues and an introduction to biostatistics and epidemiology * Practical guide to writing a protocol, getting funding for clinical research, preparing images for publication and display* Cohesive and clear presentation by authors carefully selected to teach a very popular course at NIH* Excellent companion text for courses on clinical research
Description of facilities and investigations in general clinical research centers funded by the Division of Research Resources in the United States. "Makes available to medical scientists the specialized environment necessary to conduct high-quality clinical research." Geographical arrangement by states. Each entry gives clinical research centers, major areas of investigation, personnel involved (director, investigator), and center resources. Geographical index.
First multi-year cumulation covers six years: 1965-70.