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Blood Cell Biochemistry
Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency (ADA-SCID) were transplanted with T-cells express ing adenosine deaminase (the defective enzyme in p...
Infanticide And Parental Care
First published in 1994. Infanticide is an extremely complex behavioral pattern that occurs throughout the animal kingdom and it must be considered not only in isolation but also from the viewpoint of an animal's care of its young. Infanticide and Parental Care will be of interest to zoologists, evolutionary biologists and biological anthropologists. The concept of infanticide is considered in different mammals such as humans, primates, pinnipeds, lions, dwarf mongooses and prairie dogs and in non-mammals including insects and birds. Infanticide and Parental Care also views the topic in different environmental conditions such as the natural habitat of an animal and animals kept in laboratory conditions. The wide implications of infanticide mean that this book will also be useful to historians, anthropologists, sociologists and psychologists.
A Guide To Human Gene Therapy
Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy — though still in its infancy — remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ('vector') to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study ...
Parvoviruses
For a long time, parvoviruses were mostly known in the field of veterinary medicine. Interest in these viruses broadened, however, after it was shown that one member can be harmful to humans and that some of them are endowed with oncosuppressive properties. More recently, parvovirus research received a further boost upon the realization that these agents have unique properties that make them especially suitable as vectors for a number of gene therapy applications. This timely book provides an up-to-date overview of the molecular biology of parvoviruses and their interaction with host cells and organisms as well as their pathogenic effects and potential uses as therapeutic agents. Covering th...
Peterson's Graduate Programs in Genetics, Developmental Biology, & Reproductive Biology; Marine Biology; and Microbiological Sciences
Peterson's Graduate Programs in Genetics, Developmental Biology, & Reproductive Biology; Marine Biology; and Microbiological Sciences contains a wealth of information on universities that offer graduate/professional degrees in these fields that include Genomic Sciences, Human Genetics, Molecular Genetics, Teratology, Bacteriology, Immunology, Infectious Diseases, Medical Microbiology, and Virology. Up-to-date data, collected through Peterson's Annual Survey of Graduate and Professional Institutions, provides valuable information on degree offerings, professional accreditation, jointly offered degrees, part-time and evening/weekend programs, postbaccalaureate distance degrees, faculty, studen...
Anthropological Perspectives on Aging
An in-depth and wide-ranging approach to the study of older adults in society Taking a holistic approach to the study of aging, this volume uses biological, archaeological, medical, and cultural perspectives to explore how older adults have functioned in societies around the globe and throughout human history. As the world’s population over 65 years of age continues to increase, this wide-ranging approach fills a growing need for both academics and service professionals in gerontology, geriatrics, and related fields. Case studies from the United States, Tibet, Turkey, China, Nigeria, and Mexico provide examples of the ways age-related changes are influenced by environmental, genetic, socio...
Human Stem Cell Technology and Biology
Human Stem Cell Technology & Biology: A Research Guide and Laboratory Manual integrates readily accessible text, electronic and video components with the aim of effectively communicating the critical information needed to understand and culture human embryonic stem cells. Key Features: An authoritative, comprehensive, multimedia training manual for stem cell researchers Easy to follow step-by-step laboratory protocols and instructional videos provide a valuable resource A must-have for developing laboratory course curriculums, training courses, and workshops in stem cell biology Perspectives written by the world leaders in the field Introductory chapters will provide background information The volume will be a valuable reference resource for both experienced investigators pursuing stem cell and induced pluripotent stem cell research as well as those new to this field.
Iraq
This paper discusses Iraq’s First Review of the Three-Year Stand-by Arrangement (SBA) and Financing Assurances Review, and Requests for Waivers of Nonobservance and Applicability of Performance Criteria (PCs). Two PCs at end September appear to have been met on the basis of preliminary unaudited data. One PC at end-June 2016 was missed. One continuous PC was missed. Completion of some structural benchmarks was delayed, but progress is being made for each. Hence, program performance has been mixed, but understandings on sufficient corrective actions have been reached to put the program back on track. The IMF staff recommends completion of the first review under the SBA and the financing assurances review and modification of the PCs and related rephrasing.
