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Stem Cells And Regenerative Medicine
Stem cells have the ability to differentiate into cells that are found throughout the body. This fundamental property of stem cells suggests that they can potentially be used to replace degenerative cells within the body, and regenerate the functional capacity of organ systems that have deteriorated because of disease or aging. This authoritative textbook provides an overview of the latest advances in the field of stem cell biology, spanning topics that include nuclear reprogramming, somatic cell cloning, and determinants of cell fate; embryonic stem cells for hematopoietic and pancreatic repair; adult stem cells for cardiovascular, neural, renal, and hepatic repair; and manufacturing of stem cells for clinical use.
Handbook of Cardiac Anatomy, Physiology, and Devices
the Lillehei Heart Institute in their funding of illustrator Martin Finally, I would like to thank my family and friends for their Finch, who prepared several of the original figures; Gary support of my career and their assistance over the years. Without Williams for his computer expertise and assistance with such encouragement, I would not have even dreamed of taking on numerous figures; William Gallagher and Charles Soule, who such an ambitious project. Specifically, I would like to thank my made sure the laboratory kept running smoothly while many of wife Marge, my three daughters, Maria, Jenna, and Hanna, my us were busy writing or editing; Dick Bianco for his support of morn Irene, and ...
Biomaterials and Bioactive Molecules to Drive Differentiation in Striated Muscle Tissue Engineering
Tissue engineering is an innovative, multidisciplinary approach which combines (bio)materials, cells and growth factors with the aim to obtain neo-organogenesis to repair or replenish damaged tissues and organs. The generation of engineered tissues and organs (e. g. skin and bladder) has entered into the clinical practice in response to the chronic lack of organ donors. In particular, for the skeletal and cardiac muscles the translational potential of tissue engineering approaches has clearly been shown, even though the construction of this tissue lags behind others given the hierarchical, highly organized architecture of striated muscles. Cardiovascular disease is the leading cause of death...
Mouse Development
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.*Broad-based overview of mouse development from fundamental to specialist levels*Extensive coverage of a wide range of developmental mutations of the mouse*Excellent benchmark illustrations of brain, craniofacial, gut and heart development*In-depth experiment-based assessment of concepts in mammalian development*Focus on models of specific relevance to human development*Comprehensive reference to key literature and electronic databases related to mouse development*High-quality full-color production
In Search of In Vivo MSC
The concept of multipotent mesenchymal stromal cells (MSCs) arose from the work of A.J. Friedenstein and coworkers in which the authors observed that culturing human bone marrow (BM) cell suspensions, in plastic dishes, lead to isolation of proliferating adhered colonies of fribroblastoid cells able to differentiate into chondrocytes or osteoblasts, in vitro and in vivo. Authors firstly described these cells as colony forming units of fibroblastoid cells (CFU-Fs) referring to their ability to form large colonies on plastic surfaces. The acronymous “MSC” became popular after the work of A.I. Caplan et al in 1991 where the authors proposed that in adult BM, a population of stem cells could...
Tokyo Cocktails
Tokyo Cocktails is an elegant collection of over 100 recipes inspired by the Eastern Capital. With over 13.5 million residents squeezed in to 845 square miles, Tokyo stands as one of the world’s most beguiling cities. On the surface, it appears to be nothing but towering buildings and glaring lights. But once you get to know the city, its 23 wards reveal hidden alleyways, along many of which you can find singular drinking establishments. Tokyo Cocktails takes you inside the city’s best bars and introduces you to bartenders and mixologists conjuring up drinks that reflect the city’s essence, namely how thousands of years of tradition fuse with myriad contemporary influences. Inside this...
