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Genomics of Pathogens and Vectors
We are delighted to announce a thematic issue focused on the molecular epidemiology of pathogens and vectors of disease. In the last decades, genomics has revolutionized many areas of science, technology, and health by enlightening our understanding of the intricate molecular biology of pathogens and vectors. Despite these advances viral, bacterial, fungal, and parasitic pathogens still cause huge economic and health losses around the world. Moreover, there is compelling evidence of an expansion of their impact linked to global warming, anthropogenic activities and/or limitations in control strategies. Vectored pathogens are also highly relevant, causing diseases with severe morbidity and mortality such as malaria, dengue fever and schistosomiasis. The expanding geographical reach of vectors due to adaptation and/or climate change is leading to outbreaks in previously unaffected areas. Substantial challenges remain to track and trace pathogens and vectors through molecular signatures in order to understand their impact to human and animal health in different environments.
Lifecycles of Pathogenic Protists in Humans
This volume covers the most important parasitic protists that are known to infect humans. The pathogens discussed cause diseases like toxoplasmosis, malaria, cryptosporidiosis, leishmaniasis, amoebiasis, trichomoniasis, and giardiasis. Readers from microbiology will appreciate the special focus on protist cell biology. As demonstrated in several of the chapters, these parasites are characterized by peculiar structures and organelles that cannot be found in mammalian cells – even though both are eukaryotic. The book employs light and electron microscopy to display the changing morphology in various stages of parasitic development. In turn, the results are supplemented by transcriptome and proteome profiles that help to describe how these changes take place on a molecular level. Both researchers and clinicians from tropical medicine will find essential and practically applicable background information on these increasingly important pathogens.
Science
A weekly record of scientific progress.
