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Enfermedad tromboembólica venosa
La enfermedad tromboembólica venosa se encuentra entre las primeras causas de morbimortalidad en el mundo; este padecimiento engloba dos entidades nosológicas: la trombosis venosa profunda y el embolismo pulmonar, el cual es potencialmente fatal. Se estima que la mortalidad anual en Estados Unidos oscila entre 50 000 y 200 000 casos. El diagnóstico y el tratamiento se establecen únicamente en 30% de los casos, siendo la mortalidad en este grupo de 2 a 8%; para el grupo sin diagnóstico emortalidad el estimado de mortalidad asciende a 30%. Estas estadísticas no han sido modificadas en las últimas tres décadas. En la obra se validan los métodos diagnósticos, la evaluación pronostica ...
Peptidomics
This volume describes protocols for basic state-of-the-art approaches in the field of peptidomics. Most of these approaches are independent of the instruments used for analysis and can easily be adapted for equipment that is available in a typical proteomics facility. Chapters detail many of the basic techniques used to detect and identify peptides, methods for the relative quantitation of peptides between samples using isotopic labels or label-free approaches, and biological species as well as sample types. Written in the highly successful format of the Methods in Molecular Biology series, each chapter includes an introduction to the topic, a list of the necessary materials and reagents, reproducible step-by-step laboratory protocols, and tips on troubleshooting common problems and avoiding pitfalls. Authoritative and practical, Peptidomics: Methods and Strategies provides useful guidance for studies in the rapidly growing field of peptidomics.
Estrogen Receptors
"This 8-chapter book is written by experts from China, Mexico, Portugal, United Kingdom and the United States of America. The book is focused on estrogen receptor structure, functions and clinical significance. Though we are unable to address all aspects of the estrogen receptors, we have analysed and discussed estrogen receptors or their isoforms in some major estrogen receptor-related disorders including cancers, endocrine diseases, respiratory diseases and obesity. The information provided by this book should aid our understanding the role of estrogen receptors in human diseases. This book will be of great value not only for clinicians interested in estrogen receptor-related diseases but also for basic scientists working in the field of estrogen receptors"--
Crystallization of Nucleic Acids and Proteins
Crystallography is the major method of determining structures of biological macromolecules yet crystallization techniques are still regarded as difficult to perform. This new edition of Crystallization of Nucleic Acids and Proteins: A Practical Approach continues in the vein of the first edition by providing a detailed and rational guide to producing crystals of proteins and nucleic acids of sufficient quantity and quality for diffraction studies. It has been thoroughly updated to include all the major new techniques such as the uses of molecular biology in structural biology (maximizing expression systems, sequence modifications to enable crystallization, and the introduction of anomalous s...
IBM SPSS by Example
The updated Second Edition of Alan C. Elliott and Wayne A. Woodward’s "cut to the chase" IBM SPSS guide quickly explains the when, where, and how of statistical data analysis as it is used for real-world decision making in a wide variety of disciplines. This one-stop reference provides succinct guidelines for performing an analysis using SPSS software, avoiding pitfalls, interpreting results, and reporting outcomes. Written from a practical perspective, IBM SPSS by Example, Second Edition provides a wealth of information—from assumptions and design to computation, interpretation, and presentation of results—to help users save time, money, and frustration.
Recent Advances in Game Theory and Applications
This contributed volume contains fourteen papers based on selected presentations from the European Conference on Game Theory SING11-GTM 2015, held at Saint Petersburg State University in July 2015, and the Networking Games and Management workshop, held at the Karelian Research Centre of the Russian Academy of Sciences in Petrozvavodsk, Russia, also in July 2015. These papers cover a wide range of topics in game theory, including recent advances in areas with high potential for future work, as well as new developments on classical results. Some of these include A new approach to journal ranking using methods from social choice theory; A differential game of a duopoly in which two firms are co...
Biology of Myelomonocytic Cells
Myelomonocytes are the multipotent cells in the stage of blood cell differentiation, which mainly comprise blood monocytes, tissue macrophages and subset of dendritic cells. Actually, their position and ability of judgement of the health of tissue or organ environment are the key initiators of tissue-specific immune response in a local and global fashion. Interestingly, the morpho-functional aspects of this group of cells vary to a wide range with their positional diversity. Their ability to communicate or represent the tissue microenvironment to the peripheral immune system and efficiency to engage the system to effector activation hold the key for a successful immune endeavour. The present volume shows some glimpses of such an extensive area of current immunology research.
Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9
Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes current literature on a variety of topics: -the utility of exogenous and endogenous neural stem cells in spinal cord injury -somatic cells for human induced pluripotent stem cells (iPSCs) -reactive oxygen species (ROS) mediated cellular signaling for stem cell differentiation -the therapeutic potential of microRNAs in cardiac diseases -stem cell therapy for the treatment of malaria
