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Reviewed here is the current knowledge of proton transport mechanisms in mammals. The emphasis is on gastric acid secretion and the role of the H+, K+-ATPase, but molecular and cellular information on other P-, V- and F-type H+-ATPases, in bone, kidney, plants and yeast, as well as other cation ATPases, are included for important comparisons. The role of proton/anion antiports, symports and channels in proton transport is discussed. Further attention is given to the regulation of proton transport mechanisms and cellular mechanisms to resist damage from highly acidic environments.
This volume brings together the Perspectives and Topical Reviews published during 2001 in The Journal of Physiology, with the intention of making their content as accessible as possible to both students and researchers in physiology. The Journal of Physiology publishes original research papers that illustrate new physiological principles and mechanisms. It is among the most rapidly published journals in its field, with one of the highest citation indexes in physiology.
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Brings together the Perspectives and Topical Reviews published during 1998 in The Journal of Physiology.
This volume brings together the Perspectives and Topical Reviews published during 2000 in The Journal of Physiology, with the intention of making their content as accessible as possible to both students and researchers in physiology. The Journal of Physiology publishes original research papers that illustrate new physiological principles and mechanisms, with an emphasis on human and mammalian physiology. It is among the most rapidly published journals in its field, and has one of the highest citation indexes in physiology.
Brings together the Perspectives and Topical Reviews published during 1999 in The Journal of Physiology.
This volume arose from the scientific program of the XIIth International Congress of Pharmacology, held in Montreal, Canada, July 24-29, 1994. The scientific program included plenary lectures and symposia, in addition to poster presentations and colloquia. The abstracts of the Congress presentations were published as .supplement 1 of volume 72 by the Cana dian Journal of Physiology & Pharmacology. The Congress organizers sought a more expansive treatment of the Congress proceedings and appointed Dr. A. Claudio Cuello to coordinate preparation of the present volume; Dr. Brian Collier was chair of the scientific program committee and, thus, also collaborated on this work. The objective that we...
The Carbohydrate Bioengineering Meeting held in Elsinore, Denmark, April 23-26, 1995, gathered 230 scientists, mostly from Europe, with interest in carbohydrate analysis and structure; carbohydrates in medicine and glycopathology; structure, function, application, and protein engineering of carbohydrate active enzymes; oligo- and polysaccharides of industrial interest; and production of carbohydrate containing new materials. The first chapters address glycoconjugates as modulatory and recognition molecules, structure determination using NMR and mass spectrometry, and microdialysis-chip enzyme-based sensors. Active site mutations coupled with crystal structures and synthetic substrate analogue interactions as well as new three-dimensional structures and binding domains for biotechnological applications are included in the chapters. Carbohydrate active enzymes turned out to be a predominant topic. The rapid development in glycobiology and glycotechnology has resulted in an enormous increase in our knowledge on the structure conversion, and application of carbohydrates in industry and medicine.
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