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Notch Signaling
Notch signaling is an evolutionarily conserved pathway in multicellular organisms that regulates cell-fate determination during development and in stem cells. This volume, which is part of the Current Topics in Developmental Biology series, covers topics such as Notch signaling in cardiac development and disease and Notch in stem cells. International authors provide researchers with an overview and synthesis of the latest research findings and contemporary thought in the area. - Covers topics such as Notch signaling in cardiac development and disease, and Notch in stem cells - International authors provide researchers with an overview and synthesis of the latest research findings and contemporary thought in the area
Macro Roles for MicroRNAs in the Life and Death of Neurons
The discovery of microRNAs has revealed an additional level of fine tuning of the genome and how genes are used again and again in different combinations to generate the complexity that underlies for instance the brain. This book examines this field.
‘A Truly Golden Handbook’
What would the ideal society of the future look like? In 1516, the eminent English humanist Thomas More tried his hand at imagining a perfect society on a distant island. His Utopia was published in the Flemish town of Leuven, home of a university that was established almost a century earlier. 500 years later, scholars of this university revisit More’s best-known work and reflect on the ideal society of the future, using the scientific insights of today, including perspectives which More could never have imagined. What will our cities look like a hundred years from now? How will stem cell research and 3D printing change the world? Will we be able to cure all diseases? Will we be traveling ...
Alzheimer's Disease
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
My Father's Brain
There may be up to 10 million Indians living with Alzheimer's disease or related dementias, and that number is expected to increase dramatically in the next few decades. What is it like to live with and amid this increasingly prevalent condition-an affliction that some fear more than death? In My Father's Brain, the distinguished physician and author Sandeep Jauhar sets his father's descent into Alzheimer's alongside his own journey toward understanding this disease and how it might best be coped with, if not cured. In an intimate memoir rich with humour and heartbreak, Jauhar relates how his immigrant father and extended family felt, quarrelled, and found their way through the dissolution o...
Alzheimer's Disease Research Guide
Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer's disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer's research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpen...
Winter's End
Arguably among the worst of all medical afflictions, the dementias slowly destroy one's personality, take a tremendous emotional, physical, and financial toll on patients and families, and are irreversible and inexorably fatal. Winter's End: Dementia and Its Life-Shortening Options is constructed around a lengthy and detailed nonfiction account that is layered with the voices of approximately 100 palliative medicine practitioners, legal scholars, bioethicists, social workers, nurses, neurologists, psychiatrists, and other authorities from North America and Europe. This book explores how and when one might prepare to foreshorten life after being diagnosed with a dementing illness, while not i...
Lectures for the XXIst Century
The university is a nerve centre of society. This glimpse behind the scenes of the laboratories, workshops and classrooms of KU Leuven reveal what preoccupies scientists today, and how their ideas and discoveries impact our world. This second annual series of lectures in English includes such highlights as J.J. Cassiman on Genetics and Genomics, R. Merckx on Food in Africa, G. Verbeeck on The Future of History, and a great deal more.
