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Published with the New York Academy of Sciences A timely, broad-ranging exploration of the neurobiological basis and molecular mechanisms of migraines Migraines impact the lives of a significant portion of the world's population, afflicting sufferers with severe pain, nausea, and often visual impairment. The WHO views migraines as an important public health issue, and ranks them in its top twenty most disabling illnesses. Neurobiological Basis of Migraine reviews the latest advances made in our understanding of the primary basic mechanisms of migraine headache and provides valuable insights into how these findings are being translated into novel treatment and prevention strategies around the...
The period treated in this volume is highlighted by the slow retreat of nomadism and the progressive increase of sedentary polities owing to a fundamental change in military technology: Furthermore, this period certainly saw a growing contrast in the pace of economic and cultural progress between Central Asia and Europe. The internal growth of the European economies and the influx of silver from the New World gave Atlantic Europe an increasingly important position in world trade and caused a major shift in inland Asian trade. Thus, 1850 marks the end of the total sway of pre-modern culture as the extension of colonial dominance was accompanied by the influx of modern ideas.
Cemal Kafadar offers a much more subtle and complex interpretation of the early Ottoman period than that provided by other historians. His careful analysis of medieval as well as modern historiography from the perspective of a cultural historian demonstrates how ethnic, tribal, linguistic, religious, and political affiliations were all at play in the struggle for power in Anatolia and the Balkans during the late Middle Ages. This highly original look at the rise of the Ottoman empire—the longest-lived political entity in human history—shows the transformation of a tiny frontier enterprise into a centralized imperial state that saw itself as both leader of the world's Muslims and heir to the Eastern Roman Empire.
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This book provides a wide-ranging overview of the current state of tourist destination management and presents important recent research in the field. Contemporary theoretical and methodological approaches to management and marketing are discussed, and innovative practices with respect to both urban and rural destinations are described with the aid of many interesting case studies from across Europe and beyond. In addition, the volume addresses key issues such as governance, cooperation, the use of social media, and sustainability. A variety of influences on tourism development are examined, and efficient strategies for making destinations distinct are explored. The book will be a welcome addition and update to the existing literature and will be of interest to academics and practitioners alike.
Teaching Anatomy: A Practical Guide is the first book designed to provide highly practical advice to both novice and experienced gross anatomy teachers. The volume provides a theoretical foundation of adult learning and basic anatomy education and includes chapters focusing on specific issues that teachers commonly encounter in the diverse and challenging scenarios in which they teach. The book is designed to allow teachers to adopt a student-centered approach and to be able to give their students an effective and efficient overall learning experience. Teachers of gross anatomy and other basic sciences in undergraduate healthcare programs will find in this unique volume invaluable informatio...
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