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More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
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This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical applica...
Established as one of the world's most widely read gynecology texts, Clinical Gynecologic Endocrinology and Infertility is now in its Seventh Edition. In a clear, user-friendly style enhanced by abundant illustrations, the book provides a complete explanation of the female endocrine system and its disorders and offers practical guidance on evaluation and treatment of female endocrine problems and infertility. Coverage includes the latest information on contraception and infertility and new guidelines on hormone replacement therapy during menopause. An eminent reproductive endocrinologist, Marc Fritz, MD, joins Dr. Speroff for this edition.
This book provides a comprehensive but concise overview on the economically important emerging cattle pox virus derived Lumpy Skin Disease, including the characteristics of causative agent, description of clinical signs in cattle, pathology and histopathology, immunity, geographical distribution, epidemiology and transmission pathways, control and eradication of the disease. In addition the recent developments in vaccination, mathematical modeling and risk assessment are discussed. Lumpy Skin Disease currently spreads aggressively across the Middle and Near East. The first incursion to the European Union territory occurred in Greece in autumn 2015. The book targets clinicians and field veterinarians in Lumpy Skin Disease affected regions, veterinary authorities as well as advanced students in veterinary medicine and virology.
Worldwide, individuals are living longer. As such, the number of older adults in society is increasing. By 2050, it is estimated that there will be more than two billion individuals aged over 60. This aging population is associated with an anticipated increase in the burden of the leading causes of death in modern societies, including chronic and degenerative diseases that are largely driven by age-related declines in physiological function. Physical activity is an essential regulator of energy homeostasis and helps improve metabolic health. In fact, it is well known that regular exercise lowers the risk of a broad variety of health problems, such as cardiovascular disease, type 2 diabetes, and cancer in the aged. The beneficial effect of exercise is particularly evident in older people, but it is present in all stages of life, from children to the elderly. In this regard, regular exercise and physical activity are considered key first line strategies for a healthy life.