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Adolescent Health and Wellbeing
This book presents a detailed and updated review of the widespread changes that take place during adolescence, adopting a preventive perspective that reflects physical, social, cognitive, and emotional changes. It addresses a broad range of aspects, including: the preventive programs and their systemic effects; the role of environment in influencing the healthy behaviors of adolescents and young adults; the use of e-Health technology in health and behavioral interventions for adolescents; and the clinical and prognostic implications of primordial prevention in healthy adolescents. All of these elements are subsequently reviewed using a multidimensional approach, in order to offer extensive i...
Metabolic Responses and Adaptations to Exercise
Worldwide, individuals are living longer. As such, the number of older adults in society is increasing. By 2050, it is estimated that there will be more than two billion individuals aged over 60. This aging population is associated with an anticipated increase in the burden of the leading causes of death in modern societies, including chronic and degenerative diseases that are largely driven by age-related declines in physiological function. Physical activity is an essential regulator of energy homeostasis and helps improve metabolic health. In fact, it is well known that regular exercise lowers the risk of a broad variety of health problems, such as cardiovascular disease, type 2 diabetes, and cancer in the aged. The beneficial effect of exercise is particularly evident in older people, but it is present in all stages of life, from children to the elderly. In this regard, regular exercise and physical activity are considered key first line strategies for a healthy life.
Antioxidants in Sport Nutrition
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Ischemic Heart Disease
This book describes the different aspects of ischemic heart disease, one of the leading causes of death in industrialized countries, and whose growing prevalence represents a major challenge in terms of short- and long-term management and surveillance. This volume offers a comprehensive discussion of the state-of-the-art diagnostic imaging options, of disease risk stratification, selection of candidates for surgical intervention, percutaneous revascularitation, mechanical assist devices implantation. Recently, the morbidity and mortality of ischaemic heart disease have substantially improved because of the progress in therapeutic strategies, represented by the dramatic evolution of percutane...
Advances in Clinical Chemistry
Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.
Biomarker Validation
Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.
Metal Nanocomposites in Nanotherapeutics for Oxidative Stress-Induced Metabolic Disorders
This book highlights the role and mechanism of different metal nanocomposites toward oxidative stress-induced metabolic disorders including metabolic pathways affected by oxidative stress and related pathophysiology. The book includes an illustrative discussion about the methods of synthesis, characterization, and biomedical applications of metal nanocomposites. It focuses on the therapeutic approaches for metabolic disorders due to oxidative stress by nano delivery systems. Moreover, the book includes chapters on nanotherapeutic approaches toward different diseases, including diabetes mellitus, obesity, cardiovascular disorders, cancers, and neurodegenerative diseases such as Alzheimer's di...
Oxidative Stress in Heart Diseases
This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
