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Behavioral Toxicology
Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major...
Introduction to Neurobehavioral Toxicology
Introduction to Neurobehavioral Toxicology: Food and Environment examines the effects of chemicals on the central and peripheral nervous system and the subsequent changes in behavior, with a focus on the toxicity of food components and behavioral effects of environmental toxicants. Topics addressed include acute and chronic effects; reversible and
Neurobehavioral Toxicity
In establishing how certain chemicals can cause behavioural disorders, the process of neurotoxicity risk assessment poses significant challenges to every discipline within neuroscience. In this volume, leaders from industrial, academic, and government settings share insights on behavioural measurement in neurotoxicity risk assessment, and address the critical scientific issues arising from the expanding role of neurobehavioral toxicology in public policy development.; The authors set out to provide a comprehensive and authoritative review of current methods in the analysis and interpretation of neurobehavioural toxicology. Coverage begins with a discussion of criteria for determining neurotoxic potential. The next section examines neurobehavioural evaluations in developmental neurotoxicity. Subsequent sections focus on activity and observational data and applications of schedule-controlled operant behaviour in toxicity testing. The contributors address controversies surrounding the suitability and interpretation of procedures designed for neurotoxicological assessments. Some case studies are also included.
Behavioural Ecotoxicology
Behavioural ecotoxicology is an emerging field dealing with the effects of environmental pollutants on the behaviour of animals. Behavioural techniques derived from experimental psychology, behavioural pharmacology and neurotoxicology are applied to detect and characterise changes in animals living in the environment exposed to various pollutants. Behavioural effects are then interpreted in an ecological context considering the long-term relevance of these changes at both the individual and population level.
Risk Assessment for Neurobehavioral Toxicity
After three decades of research, neurobehavioral toxicity is now acknowledged as a significant outcome of chemical exposure. Its health and economic costs may exceed those by cancer by substantial amounts. This new perspective has been accompanied by efforts designed to explore the responsible mechanisms, to design applicable risk assessment procedures, and to determine the consequent policy implications. This publication includes 25 papers from international experts and includes: human neurobehavioral toxicity; animal behavioral methods; selected model compounds; and risk assessment.
