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Polychlorinated biphenyls (PCBs) have been produced commercially since be fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen erally biologically inactive even though industrial exposure had demonstrated he patic and dermatological effects (Fishbein,...
This a companion volume to Environmental Health Criteria no. 140: Polychlorinated biphenyls & terphenyls (2nd ed.). For the International Programme on Chemical Safety (a collaborative programme of UNEP, ILO & WHO
The concern about environmental toxins is ever increasing, as is the need for sound scientific information. The "Environmental Toxin Series" is dedicated to the publication of comprehensive reviews and monographs on compounds or classes of chemicals which are of importance in environmental toxicology. The series is designed to serve as a background of information for scientific investigation as well as risk analysis and political decision making. The main aim of the series is to describe in as complete a way as possible all potentially hazardous chemicals from the point of view of chemistry, ecology, toxicology, risk analysis and regulatory implications. From time to time conference proceedings on important and urgent topics will be included in the series. We thank the members of the editorial board for their enthusiastic support.
Polychlorinated Biphenyls (PCBs) are synthetic chlorinated hydrocarbon compounds, produced commercially since 1929 for use in a variety of products including plastics and adhesives, surface coatings, inks, flame retardants, pesticides and paints. PCBs are environmentally persistent, and accumulate in the food chain. They are designated by the Stockholm Convention on Persistent Organic Pollutants as persistent pollutants, and many countries have severely restricted or banned the production of PCBs. This report evaluates the effects of PCBs on human health, caused due to exposure by inhaling contaminated air or ingesting contaminated food and water.