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Small Molecules in Oncology
Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein kinase inhibitors are attracting a vast amount of investigational attention. This textbook, written by acknowledged experts, provides a broad overview of the small molecules currently used for the treatment of malignant diseases and discusses interesting novel compounds that are in the process of clinical development to combat cancer.
Cancer Research
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Das Blaue Buch
Bewährt, topaktuell und grundlegend überarbeitet erscheint bereits die 5. Auflage des Blauen Buches. Das Blaue Buch steht seit Jahren für eine in der Praxis einfach handhabbare Sammlung von Chemotherapie-Protokollen zur Behandlung von Krebspatienten mit soliden und hämatologischen Tumoren. Wie gewohnt sind auf einen Blick Detailinformationen zu Chemotherapie, Begleitmedikation, Notfallsituationen, Nebenwirkungen, Kontrollen, supportiven Therapien sowie Zusatzinformationen für eine sichere Applikation aufgeführt. Die über 400 umfassend ausgearbeiteten und jahrelang in der Praxis etablierten Behandlungsprotokolle, übersichtlich nach Tumorentitäten und Indikationen geordnet, sind auf B...
Clinch
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KODEN
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Controlled Human Inhalation-Exposure Studies at EPA
The U.S. Environmental Protection Agency (EPA) has a mission and regulatory responsibility to protect human health and the environment. EPA's pursuit of that goal includes a variety of research activities involving human subjects, such as epidemiologic studies and surveys. Those research activities also involve studies of individuals who volunteer to be exposed to air pollutants intentionally in controlled laboratory settings so that measurements can be made of transient and reversible biomarker or physiologic responses to those exposures that can indicate pathways of toxicity and mechanisms of air-pollution responses. The results of those controlled human inhalation exposure (CHIE) studies,...
Thoracic Malignancies
Thoracic Malignancies: Thoracic Malignancies is the first title in Radiation Medicine Rounds. These tumors take more lives than any others and they are among the most preventable of tumors. Thus it is crucial for the practitioner to be up-to-date on the latest insights regarding their management. Thoracic Malignancies addresses the multi-disciplinary nature of the care of these tumors. There is representation from radiation oncology, medical oncology, and surgery ensuring a well-rounded summarization of current practice. Included are chapters on lung cancer, esophageal cancer, and thymomas providing coverage of the vast majority of thoracic tumors. The multi-disciplinary nature of the articl...
