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Retinal Disorders: Genetic Approaches to Diagnosis and Treatment, Second Edition
The retina is a layer of neural tissue that lines the inner eye and captures visual stimuli. This volume provides an update on retinal diseases, describing the genetic and pathophysiological basis of the diseases and advances in strategies to treat them. Topics covered in this essential volume include: - Genetics and pathophysiology of inherited retinal degenerations - Gene therapies - Visual prosthesis - Cell-based therapies - Preparing clinical trials, and outcome measures
Managing Nano-Bio-Info-Cogno Innovations
With the convergence of Nanotechnology, Biotechnology, Information technology and Cognitive science (NBIC) fields promising to change our competitive, operational, and employment landscape in fundamental ways, we find ourselves on the brink of a new technological and science-driven business revolution. The already emerging reality of convergence is to be found in genomics, robotics, bio-information and artificial intelligence applications, such as: • Self-assembled, self-cleaning and self-healing manufactured materials and textiles, and much stronger, lighter and more customizable structural materials, • Miniature sensors allowing unobtrusive real-time health monitoring and dramatically ...
Cellular Nanoscale Sensory Wave Computing
This book is loosely based on a Multidisciplinary University Research Initiative (MURI) project and a few supplemental projects sponsored by the Of?ce of Naval Research (ONR) during the time frame of 2004–2009. The initial technical scope and vision of the MURI project was formulated by Drs. Larry Cooper and Joel Davis, both program of?cers at ONR at the time. The unifying theme of this MURI project and its companionefforts is the concept of cellular nonlinear/neuralnetwork (CNN) technology and its various extensions and chip implementations, including nanoscale sensors and the broadening ?eld of cellular wave computing. In recent years, CNN-based vision system drew much attention from vis...
The New Visual Neurosciences
A comprehensive review of contemporary research in the vision sciences, reflecting the rapid advances of recent years. Visual science is the model system for neuroscience, its findings relevant to all other areas. This essential reference to contemporary visual neuroscience covers the extraordinary range of the field today, from molecules and cell assemblies to systems and therapies. It provides a state-of-the art companion to the earlier book The Visual Neurosciences (MIT Press, 2003). This volume covers the dramatic advances made in the last decade, offering new topics, new authors, and new chapters. The New Visual Neurosciences assembles groundbreaking research, written by international a...
Principles of Neurobiology
Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.
7 Keys to Freedom
If you feel stuck financially, find yourself procrastinating on your dreams, or just want to live more freely and abundantly in every area of your life, then you may need to give your "mental muscles" a workout. Just as your body is equipped with physical muscles, your mind is equipped with "mental muscles". However, most of us are not aware that our thinking determines the circumstances in our lives. You need to strengthen your "mental muscles"-imagination, memory, reason, perception, intuition and will-to create a life full of passion and abundance. The authors, an international team of coaches share anecdotes from their lives, the latest discoveries in neuroscience, and practical action s...
Concepts and Challenges in Retinal Biology
In August 2000 a Festschrift was held at the Marine Biological Laboratory, Woods Hole, Massachusetts to celebrate the career of Professor John E. Dowling on the occasion of his 65th birthday. Containing contributions from more than 50 of John's colleagues, representing a Who's Who of the vision research community, this work not only provides a memento of the occasion, but will hopefully serve as a basic reference for future researchers in retinal biology. The volume is divided somewhat arbitrarily into seven areas of retinal research containing chapters that present in some cases a broad overview of a particular topic, and in others an account of current research and studies in progress. These chapters exemplify the richness, diversity, and excitement of contemporary retinal research. They also remind us of how much more needs to be done before we understand fully the interrelationship between retinal neurons, the complex interactions between neurons and glial cells, and the mechanisms that govern retinal development. A final chapter contributed by John Dowling provides an overview of past accomplishments, and offers some future perspectives on retinal research in the 21st century.
Hierarchical Neural Networks for Image Interpretation
Human performance in visual perception by far exceeds the performance of contemporary computer vision systems. While humans are able to perceive their environment almost instantly and reliably under a wide range of conditions, computer vision systems work well only under controlled conditions in limited domains. This book sets out to reproduce the robustness and speed of human perception by proposing a hierarchical neural network architecture for iterative image interpretation. The proposed architecture can be trained using unsupervised and supervised learning techniques. Applications of the proposed architecture are illustrated using small networks. Furthermore, several larger networks were trained to perform various nontrivial computer vision tasks.
Applications of Chimeric Genes and Hybrid Proteins, Part B: Cell Biology and Physiology
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Retinal Degenerative Diseases
The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the “best” and “most important” meetings in the field. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic...
