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Genetic Data Analysis II
Genetic Data Analysis II details the statistical methodology needed to draw inferences from discrete genetic data. An emphasis is given to permutation tests, and developments in phylogenetic tree construction are reviewed.
Interpreting DNA Evidence
Interpretation of DNA profile matches depends on the use of statistical weights. This text provides the background information in statistics and genetics for the reader to arrive at these weights.
Forensic DNA Profiling Protocols
This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here -- many from laboratories around the world -- also discuss how to interpret the results in cases of unknown identity and disputed parentage.-- Covers all steps from extraction of human DNA through to analysis and interpretation-- Takes advantage of new methodologies such as capillary electrophoresis-- Clear step-by-step instructions ensure unfailing reproducibility.
About Method
Scientists’ views on what makes an experiment successful have developed dramatically throughout history. Different criteria for proper experimentation were privileged at different times, entirely new criteria for securing experimental results emerged, and the meaning of commitment to experimentation altered. In About Method, Schickore captures this complex trajectory of change from 1660 to the twentieth century through the history of snake venom research. As experiments with poisonous snakes and venom were both challenging and controversial, the experimenters produced very detailed accounts of their investigations, which go back three hundred years—making venom research uniquely suited f...
Proceedings of the Fourth Seattle Symposium in Biostatistics: Clinical Trials
This volume contains a selection of chapters base on papers presented at the Fourth Seattle Symposium in Biostatistics: Clinical Trials. The symposium was held in 2010 to celebrate the 40th anniversary of the University of Washington School of Public Health and Community Medicine. It featured keynote lectures by David DeMets and Susan Ellenberg and 16 invited presentations by other prominent researchers. The papers contained in this volume encompass recent methodological advances in several important clinical trials research, such as biomarkers, meta-analyses, sequential and adaptive clinical trials, and various genetic bioinformatic techniques. This volume will be a valuable reference for researchers and practitioners in the field of clinical trials.
The Seven Deadly Sins of Psychology
Why psychology is in peril as a scientific discipline—and how to save it Psychological science has made extraordinary discoveries about the human mind, but can we trust everything its practitioners are telling us? In recent years, it has become increasingly apparent that a lot of research in psychology is based on weak evidence, questionable practices, and sometimes even fraud. The Seven Deadly Sins of Psychology diagnoses the ills besetting the discipline today and proposes sensible, practical solutions to ensure that it remains a legitimate and reliable science in the years ahead. In this unflinchingly candid manifesto, Chris Chambers shows how practitioners are vulnerable to powerful biases that undercut the scientific method, how they routinely torture data until it produces outcomes that can be published in prestigious journals, and how studies are much less reliable than advertised. Left unchecked, these and other problems threaten the very future of psychology as a science—but help is here.
ABA Standards for Criminal Justice
"Although the Standards in this volume are considered part of the set of Third Edition ABA Criminal Justice Standards, the earlier editions did not include standards on DNA evidence. Therefore, the Standards included here are the first ABA Criminal Justice Standards on DNA Evidence."--Page iii.
A Guide to Forensic DNA Profiling
The increasingly arcane world of DNA profiling demands that those needing to understand at least some of it must find a source of reliable and understandable information. Combining material from the successful Wiley Encyclopedia of Forensic Science with newly commissioned and updated material, the Editors have used their own extensive experience in criminal casework across the world to compile an informative guide that will provide knowledge and thought-provoking articles of interest to anyone involved or interested in the use of DNA in the forensic context. Following extensive introductory chapters covering forensic DNA profiling and forensic genetics, this comprehensive volume presents a s...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Evolutionary Biology
After volume 33, this book series was replaced by the journal "Evolutionary Biology." Please visit www.springer.com/11692 for further information. The nature of science is to work on the boundaries between the known and the unknown. These boundaries shift as new methods are developed and as new concepts are elaborated (e.g., the theory of the gene, or more recently, the coalescence framework in population genetics). These tools allow us to address questions that were previously outside the realm of science, and, as a consequence, the boundary between the knowable and unknowable has shifted. A study of limits should reveal and clarify the boundaries and make sharper the set of questions. This book examines and analyzes these new limits as they are applied to evolutionary biology and population genetics. It does this by framing the analysis within four major classes of problems - establishing the fact of evolution; understanding the evolutionary pathways that led to today's biological world; mechanisms of evolutionary change (e.g., models of social behavior, sexual selection, macro evolution); and, finally, prediction.
